-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0000866105-10-000002.txt : 20100303
<SEC-HEADER>0000866105-10-000002.hdr.sgml : 20100303
<ACCEPTANCE-DATETIME>20100303152301
ACCESSION NUMBER:		0000866105-10-000002
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Securities Act Section 4(6)
FILED AS OF DATE:		20100303
DATE AS OF CHANGE:		20100303
EFFECTIVENESS DATE:		20100303

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMPLIMED CORP
		CENTRAL INDEX KEY:			0000866105
		IRS NUMBER:				860625176
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-59001
		FILM NUMBER:		10653239

	BUSINESS ADDRESS:	
		STREET 1:		4380 NORTH CAMPBELL AVENUE
		STREET 2:		SUITE 205
		CITY:			TUCSON
		STATE:			AZ
		ZIP:			85718
		BUSINESS PHONE:		520-529-1000

	MAIL ADDRESS:	
		STREET 1:		4380 NORTH CAMPBELL AVENUE
		STREET 2:		SUITE 205
		CITY:			TUCSON
		STATE:			AZ
		ZIP:			85718
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0000866105</cik>
        <entityName>AMPLIMED CORP</entityName>
        <issuerAddress>
            <street1>4380 NORTH CAMPBELL AVENUE</street1>
            <street2>SUITE 205</street2>
            <city>TUCSON</city>
            <stateOrCountry>AZ</stateOrCountry>
            <zipCode>85718</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>520-529-1000</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Chris</firstName>
                <lastName>Richied</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>M.</middleName>
                <lastName>Holliman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ronald</firstName>
                <lastName>Garren</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Harry</firstName>
                <middleName>A.</middleName>
                <lastName>George</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joel</firstName>
                <lastName>Smolen</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>T.</middleName>
                <lastName>Dorr</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Randolph</firstName>
                <lastName>Steer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steve</firstName>
                <lastName>Steinman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <lastName>Remers</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4380 North Campbell Avenue</street1>
                <street2>Suite 205</street2>
                <city>Tucson</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85718</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>46</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0000866105-10-000001</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-08-17</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>500</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>DPEC Capital, Inc.</recipientName>
                <recipientCRDNumber>10737</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>135 Fifth Avenue</street1>
                    <street2>10th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10010</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>12000000</totalOfferingAmount>
            <totalAmountSold>7142093</totalAmountSold>
            <totalRemaining>4857907</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>11</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>94250</dollarAmount>
                <isEstimate>true</isEstimate>
            </findersFees>
            <clarificationOfResponse>In addition to $94,250 the Company issued DPEC Capital a total of 234,560 warrants to purchase Series D stock.  The warrants issued include those issued in connection with a bridge loan, the proceeds of which were converted to shares of Series D.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>A portion may be used to pay accrued salaries to executives, but the exact amount, if any, is not yet determinable.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>AMPLIMED CORP</issuerName>
                <signatureName>Chris Richied</signatureName>
                <nameOfSigner>Chris Richied</nameOfSigner>
                <signatureTitle>Chief Financial Officer</signatureTitle>
                <signatureDate>2010-03-03</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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