-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 TqHG5jeo1eRx/NFD690E8vvOx/xHeroctAcqQ29UjMPbIT4poAvog5fcfuyNuGiG
 dBjjY1y3MjGWJeqs28iu8w==

<SEC-DOCUMENT>0000707511-09-000002.txt : 20090513
<SEC-HEADER>0000707511-09-000002.hdr.sgml : 20090513
<ACCEPTANCE-DATETIME>20090513161054
ACCESSION NUMBER:		0000707511-09-000002
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090513
DATE AS OF CHANGE:		20090513
EFFECTIVENESS DATE:		20090513

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			REGENERX BIOPHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000707511
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				521253406
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-70751-1P
		FILM NUMBER:		09822581

	BUSINESS ADDRESS:	
		STREET 1:		3 BETHESDA METRO CENTER
		STREET 2:		SUITE 700
		CITY:			BETHESDA
		STATE:			MD
		ZIP:			20814
		BUSINESS PHONE:		3019611992

	MAIL ADDRESS:	
		STREET 1:		3 BETHESDA METRO CENTER
		STREET 2:		SUITE 700
		CITY:			BETHESDA
		STATE:			MD
		ZIP:			20814

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ALPHA 1 BIOMEDICALS INC
		DATE OF NAME CHANGE:	19950719
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0301</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0000707511</cik>
        <entityName>REGENERX BIOPHARMACEUTICALS INC</entityName>
        <issuerAddress>
            <street1>3 BETHESDA METRO CENTER</street1>
            <street2>Suite 630</street2>
            <city>BETHESDA</city>
            <stateOrCountry>MD</stateOrCountry>
            <zipCode>20814</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(301) 280-1992</issuerPhoneNumber>
        <issuerPreviousNameList>
            <previousName>ALPHA 1 BIOMEDICALS INC</previousName>
        </issuerPreviousNameList>
        <jurisdictionOfInc>DE</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>J.J.</firstName>
                <middleName></middleName>
                <lastName>Finkelstein</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName></middleName>
                <lastName>Crockford</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>C. Neil</firstName>
                <middleName></middleName>
                <lastName>Lyons</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mauro</firstName>
                <middleName></middleName>
                <lastName>Bove</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>L. Thompson</firstName>
                <middleName></middleName>
                <lastName>Bowles</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Allan</firstName>
                <middleName></middleName>
                <lastName>Goldstein</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName></middleName>
                <lastName>Hindin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName></middleName>
                <lastName>McNay</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o RegeneRx Biopharmaceuticals, Inc.</street1>
                <street2>3 Bethesda Metro Center, Suite 630</street2>
                <city>Bethesda</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20814</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$1 - $1,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-04-30</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>N/A</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>N/A</street1>
                    <street2></street2>
                    <city>N/A</city>
                    <stateOrCountry>XX</stateOrCountry>
                    <zipCode>00000</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>MD</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>600000</totalOfferingAmount>
            <totalAmountSold>600000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>REGENERX BIOPHARMACEUTICALS INC</issuerName>
                <signatureName>/s/ C. Neil Lyons</signatureName>
                <nameOfSigner>C. Neil Lyons</nameOfSigner>
                <signatureTitle>Chief Financial Officer and Treasurer</signatureTitle>
                <signatureDate>2009-05-12</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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