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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0000945621-10-000196.txt : 20101117
<SEC-HEADER>0000945621-10-000196.hdr.sgml : 20101117
<ACCEPTANCE-DATETIME>20101117161547
ACCESSION NUMBER:		0000945621-10-000196
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(1)
FILED AS OF DATE:		20101117
DATE AS OF CHANGE:		20101117
EFFECTIVENESS DATE:		20101117

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Essex Global Life Sciences Fund, LP (a Series of Essex Specialty Pooled Funds, L.P.)
		CENTRAL INDEX KEY:			0001505786
		IRS NUMBER:				043400565
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-150594
		FILM NUMBER:		101200012

	BUSINESS ADDRESS:	
		STREET 1:		C/O ESSEX INVESTMENT MANAGEMENT CO., LLC
		STREET 2:		125 HIGH ST., 29TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		617-342-3200

	MAIL ADDRESS:	
		STREET 1:		C/O ESSEX INVESTMENT MANAGEMENT CO., LLC
		STREET 2:		125 HIGH ST., 29TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Essex Global Life Science Fund (a Series of Essex Specialty Pooled Funds, L.P.)
		DATE OF NAME CHANGE:	20101116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Essex Specialty Funds, L.P.
		DATE OF NAME CHANGE:	20101115
</SEC-HEADER>
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<TEXT>
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        <cik>0001505786</cik>
        <entityName>Essex Global Life Sciences Fund, LP (a Series of Essex Specialty Pooled Funds, L.P.)</entityName>
        <issuerAddress>
            <street1>C/O ESSEX INVESTMENT MANAGEMENT CO., LLC</street1>
            <street2>125 HIGH ST., 29TH FLOOR</street2>
            <city>BOSTON</city>
            <stateOrCountry>MA</stateOrCountry>
            <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
            <zipCode>02110</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>617-342-3200</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>Essex Global Life Science Fund (a Series of Essex Specialty Pooled Funds, L.P.)</previousName>
            <previousName>Essex Specialty Funds, L.P.</previousName>
        </edgarPreviousNameList>
        <entityType>Limited Partnership</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>n/a</firstName>
                <middleName>n/a</middleName>
                <lastName>Essex Investment Managment Company, LLC</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>125 High Street, 29th Floor</street1>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>02110</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>General Partner of Essex Specialty Pooled Funds, LP (&quot;General Partner&quot;)</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName>C.</middleName>
                <lastName>McNay</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Essex Investment Management Co., LLC</street1>
                <street2>125 High Street, 29th Floor</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>02110</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
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            <relationshipClarification>Executive Officer of the General Partner</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stephen</firstName>
                <middleName>D.</middleName>
                <lastName>Cutler</lastName>
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            <relatedPersonAddress>
                <street1>c/o Essex Investment Management Co., LLC</street1>
                <street2>125 High Street, 29th Floor</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>02110</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
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            <relationshipClarification>Executive Officer of the General Partner</relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <middleName>P.</middleName>
                <lastName>McConnell</lastName>
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            <relatedPersonAddress>
                <street1>c/o Essex Investment Management Co., LLC</street1>
                <street2>125 High Street, 29th Floor</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>02110</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Officer of the General Partner</relationshipClarification>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Other Investment Fund</investmentFundType>
                <is40Act>false</is40Act>
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        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.1</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0000945621-10-000193</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>1998-04-08</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>500000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>1363466</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>4</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
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                <dollarAmount>0</dollarAmount>
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            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Essex Global Life Sciences Fund, LP (a Series of Essex Specialty Pooled Funds, L.P.)</issuerName>
                <signatureName>/s/ Deborah Coulter</signatureName>
                <nameOfSigner>Deborah Coulter</nameOfSigner>
                <signatureTitle>Chief Financial Officer of the General Partner</signatureTitle>
                <signatureDate>2010-09-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
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</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----