-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Kbtl240vBkPu1rx8gs7edU4xp90NmUReH9TOpKbcNPGWV7gF+obPWZ1xmU6QNpKi
 uPnavMdxp1Pb1s1gm13TRQ==

<SEC-DOCUMENT>0001482253-10-000001.txt : 20100127
<SEC-HEADER>0001482253-10-000001.hdr.sgml : 20100127
<ACCEPTANCE-DATETIME>20100127115747
ACCESSION NUMBER:		0001482253-10-000001
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100127
DATE AS OF CHANGE:		20100127
EFFECTIVENESS DATE:		20100127

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Predictive Biomarker Sciences, Inc.
		CENTRAL INDEX KEY:			0001482253
		IRS NUMBER:				204095667
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-138209
		FILM NUMBER:		10549660

	BUSINESS ADDRESS:	
		STREET 1:		2036 EAST HACKAMORE
		CITY:			MESA
		STATE:			AZ
		ZIP:			85213
		BUSINESS PHONE:		858-945-3406

	MAIL ADDRESS:	
		STREET 1:		2036 EAST HACKAMORE
		CITY:			MESA
		STATE:			AZ
		ZIP:			85213
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001482253</cik>
        <entityName>Predictive Biomarker Sciences, Inc.</entityName>
        <issuerAddress>
            <street1>2036 EAST HACKAMORE</street1>
            <city>MESA</city>
            <stateOrCountry>AZ</stateOrCountry>
            <zipCode>85213</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>858-945-3406</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2006</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Edward</firstName>
                <middleName>A</middleName>
                <lastName>Smith</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2036 East Hackamore</street1>
                <city>Mesa</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85213</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Brian</firstName>
                <middleName>E</middleName>
                <lastName>Smith</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1010 N. Heritage Street</street1>
                <city>Gilbert</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85234</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Paul</firstName>
                <middleName>E</middleName>
                <lastName>Kreutz</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1016 Sea Village Drive</street1>
                <city>Cardiff</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92007</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Baker</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>10115 E. Calle de las Brisas</street1>
                <city>Scottsdale</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85255</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ray</firstName>
                <lastName>Thurston</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>7702 N. Mockingbird Lane</street1>
                <city>Paradise Valley</city>
                <stateOrCountry>AZ</stateOrCountry>
                <zipCode>85253</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$1 - $1,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-01-13</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>1300</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>500000</totalOfferingAmount>
            <totalAmountSold>338132</totalAmountSold>
            <totalRemaining>161868</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>8</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>250000</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Predictive Biomarker Sciences, Inc.</issuerName>
                <signatureName>Paul E. Kreutz</signatureName>
                <nameOfSigner>Paul E. Kreutz</nameOfSigner>
                <signatureTitle>Secretary</signatureTitle>
                <signatureDate>2010-01-27</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----