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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001480722-10-000002.txt : 20100115
<SEC-HEADER>0001480722-10-000002.hdr.sgml : 20100115
<ACCEPTANCE-DATETIME>20100115113752
ACCESSION NUMBER:		0001480722-10-000002
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(7)
FILED AS OF DATE:		20100115
DATE AS OF CHANGE:		20100115
EFFECTIVENESS DATE:		20100115

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Morgan Stanley Smith Barney Crossroads 2010 Fund LP
		CENTRAL INDEX KEY:			0001480722
		IRS NUMBER:				270892981
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-137886
		FILM NUMBER:		10529354

	BUSINESS ADDRESS:	
		STREET 1:		325 N. SAINT PAUL STREET
		STREET 2:		SUITE 4900
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75201
		BUSINESS PHONE:		214-647-9500

	MAIL ADDRESS:	
		STREET 1:		325 N. SAINT PAUL STREET
		STREET 2:		SUITE 4900
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75201
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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    <primaryIssuer>
        <cik>0001480722</cik>
        <entityName>Morgan Stanley Smith Barney Crossroads 2010 Fund LP</entityName>
        <issuerAddress>
            <street1>325 N. SAINT PAUL STREET</street1>
            <street2>SUITE 4900</street2>
            <city>DALLAS</city>
            <stateOrCountry>TX</stateOrCountry>
            <zipCode>75201</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>214-647-9500</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
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        <entityType>Limited Partnership</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
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    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>P.</middleName>
                <lastName>Buser</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>John P. Buser is a President and a Managing Director of NB Crossroads 2010 Fund GP LLC, and a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Brien</firstName>
                <middleName>P.</middleName>
                <lastName>Smith</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Brien P. Smith is a Managing Director of NB Crossroads 2010 Fund GP LLC, and a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName>A.</middleName>
                <lastName>Malick</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>57 Berkeley Square, Lansdowne House</street1>
                <street2>Neuberger Berman Europe Limited</street2>
                <city>London</city>
                <stateOrCountry>X0</stateOrCountry>
                <zipCode>W1J 6ER</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Joseph A. Malick is a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Anthony</firstName>
                <middleName>D.</middleName>
                <lastName>Tutrone</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Anthony D. Tutrone is a Chief Executive Officer and Managing Director of NB Crossroads 2010 Fund GP LLC, and a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <lastName>Stonberg</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>David Stonberg is a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <lastName>Von Lehe</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Peter Von Lehe is a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jonathan</firstName>
                <lastName>Shofet</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Jonathan Shofet is a member of the investment committee.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Andrew</firstName>
                <lastName>Komaroff</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Andrew Komaroff is a Managing Director and Chief Administrative Officer of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Rees</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>605 Third Avenue</street1>
                <street2>22nd Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10158</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Michael Rees is a Managing Director of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <lastName>Frattaroli</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Christopher Frattaroli is a Senior Vice-President of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Beverly</firstName>
                <lastName>Lemond</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Beverly Lemond is a Senior Vice-President of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Blake</firstName>
                <lastName>Rice</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Blake Rice is a Senior Vice-President and Assistant Secretary of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Sean</firstName>
                <lastName>Ward</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>325 N. Saint Paul Street</street1>
                <street2>Suite 4900</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75201</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Sean Ward is a Senior Vice-President and Assistant Secretary of NB Crossroads 2010 Fund GP LLC.</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.7</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-01-06</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>MORGAN STANLEY SMITH BARNEY</recipientName>
                <recipientCRDNumber>149777</recipientCRDNumber>
                <associatedBDName>MORGAN STANLEY SMITH BARNEY</associatedBDName>
                <associatedBDCRDNumber>149777</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>2000 WESTCHESTER AVENUE</street1>
                    <city>Purchase</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10577-2530</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1000000000</totalOfferingAmount>
            <totalAmountSold>13050000</totalAmountSold>
            <totalRemaining>986950000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>12</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>1000000</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse>Estimate represents one percent of a potential one billion in Fund interests that could be sold to investors over the course of the next twelve months.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
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                <issuerName>Morgan Stanley Smith Barney Crossroads 2010 Fund LP</issuerName>
                <signatureName>John Buser</signatureName>
                <nameOfSigner>John Buser</nameOfSigner>
                <signatureTitle>See the above Clarification Box in Item #3</signatureTitle>
                <signatureDate>2010-01-14</signatureDate>
            </signature>
        </signatureBlock>
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