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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 Z3gekoyT0VyrDtSv7jeJiQ==

<SEC-DOCUMENT>0001479364-09-000003.txt : 20091230
<SEC-HEADER>0001479364-09-000003.hdr.sgml : 20091230
<ACCEPTANCE-DATETIME>20091230133718
ACCESSION NUMBER:		0001479364-09-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 504(b)(1) (not (i), (ii) or (iii))
FILED AS OF DATE:		20091230
DATE AS OF CHANGE:		20091230
EFFECTIVENESS DATE:		20091230

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centennial CyberKnife Center, LLC
		CENTRAL INDEX KEY:			0001479364
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-137301
		FILM NUMBER:		091265867

	BUSINESS ADDRESS:	
		STREET 1:		ONE PARK PLAZA
		CITY:			NASHVILLE
		STATE:			TN
		ZIP:			37203
		BUSINESS PHONE:		615-344-9551

	MAIL ADDRESS:	
		STREET 1:		ONE PARK PLAZA
		CITY:			NASHVILLE
		STATE:			TN
		ZIP:			37203

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centennial CyberKnife, LLC
		DATE OF NAME CHANGE:	20091223
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001479364</cik>
        <entityName>Centennial CyberKnife Center, LLC</entityName>
        <issuerAddress>
            <street1>250 25th Avenue North</street1>
            <city>NASHVILLE</city>
            <stateOrCountry>TN</stateOrCountry>
            <zipCode>37203</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>615-344-9551</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>Centennial CyberKnife, LLC</previousName>
        </edgarPreviousNameList>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>.</firstName>
                <lastName>HCA Health Services of Tennessee, Inc.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Park Plaza</street1>
                <city>Nashville</city>
                <stateOrCountry>TN</stateOrCountry>
                <zipCode>37203</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Managing Member</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>A.</firstName>
                <middleName>Bruce</middleName>
                <lastName>Moore, Jr.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Park Plaza</street1>
                <city>Nashville</city>
                <stateOrCountry>TN</stateOrCountry>
                <zipCode>37203</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>R.</firstName>
                <middleName>Milton</middleName>
                <lastName>Johnson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Park Plaza</street1>
                <city>Nashville</city>
                <stateOrCountry>TN</stateOrCountry>
                <zipCode>37203</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <middleName>B.</middleName>
                <lastName>Rutherford</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Park Plaza</street1>
                <city>Nashville</city>
                <stateOrCountry>TN</stateOrCountry>
                <zipCode>37203</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>04</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-12-21</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>15567</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Not applicable</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>Not applicable</street1>
                    <city>Not applicable</city>
                    <stateOrCountry>XX</stateOrCountry>
                    <zipCode>00000</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>TN</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>311340</totalOfferingAmount>
            <totalAmountSold>311340</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>311340</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>Payment to the Managing Member in consideration of dilution of its membership interest in the Issuer</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Centennial CyberKnife Center, LLC</issuerName>
                <signatureName>/s/ A. Bruce Moore, Jr.</signatureName>
                <nameOfSigner>A. Bruce Moore, Jr.</nameOfSigner>
                <signatureTitle>Senior Vice President of Managing Member</signatureTitle>
                <signatureDate>2009-12-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----