-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 uhjw11IyX40vIw1emlOvCQ==

<SEC-DOCUMENT>0001478242-09-000003.txt : 20091221
<SEC-HEADER>0001478242-09-000003.hdr.sgml : 20091221
<ACCEPTANCE-DATETIME>20091221143653
ACCESSION NUMBER:		0001478242-09-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091221
DATE AS OF CHANGE:		20091221
EFFECTIVENESS DATE:		20091221

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Quintiles Transnational Holdings Inc.
		CENTRAL INDEX KEY:			0001478242
		IRS NUMBER:				271341991
		STATE OF INCORPORATION:			NC
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-137023
		FILM NUMBER:		091252163

	BUSINESS ADDRESS:	
		STREET 1:		4820 EMPEROR BLVD.
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-998-2000

	MAIL ADDRESS:	
		STREET 1:		4820 EMPEROR BLVD.
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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    <submissionType>D</submissionType>

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        <cik>0001478242</cik>
        <entityName>Quintiles Transnational Holdings Inc.</entityName>
        <issuerAddress>
            <street1>4820 EMPEROR BLVD.</street1>
            <city>DURHAM</city>
            <stateOrCountry>NC</stateOrCountry>
            <zipCode>27703</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>919-998-2000</issuerPhoneNumber>
        <jurisdictionOfInc>NORTH CAROLINA</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>QPB Holdings Corp.</previousName>
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        <edgarPreviousNameList>
            <value>None</value>
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        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
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    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Dennis</firstName>
                <middleName>B</middleName>
                <lastName>Gillings</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>D.</middleName>
                <lastName>Ratliff</lastName>
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            <relatedPersonRelationshipList>
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                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Fred</firstName>
                <lastName>Cohen</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
                <street2>Suite 3300</street2>
                <city>Fort Worth</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>76102</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Connaughton</lastName>
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            <relationshipClarification></relationshipClarification>
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            <relatedPersonName>
                <firstName>Jonathan</firstName>
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                <lastName>Coslet</lastName>
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            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
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                <city>Fort Worth</city>
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            <relatedPersonRelationshipList>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ronald</firstName>
                <middleName>J.</middleName>
                <lastName>Wooten</lastName>
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            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <lastName>Gordon</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>111 Huntington Ave.</street1>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02199</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jack</firstName>
                <lastName>Greenberg</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
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            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Moore</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>375 Park Avenue</street1>
                <street2>Suite 3001</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10152</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Leonard</firstName>
                <lastName>Schaeffer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>301 Commerce Street</street1>
                <street2>Suite 3300</street2>
                <city>Fort Worth</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>76102</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Tan</firstName>
                <middleName>Suan</middleName>
                <lastName>Swee</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>60 B. Orchard Road #06-18, Tower 2</street1>
                <street2>The Atrium at Orchard</street2>
                <city>Singapore</city>
                <stateOrCountry>U0</stateOrCountry>
                <zipCode>238891</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Mortimer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <middleName>P.</middleName>
                <lastName>Troullis</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Derek</firstName>
                <lastName>Winstanly</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>4820 Emperor Blvd.</street1>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27703</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-12-15</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>150000000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>525000000</totalOfferingAmount>
            <totalAmountSold>525000000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>Total Amount Sold includes a 4.25% original issue discount.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>2</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>93848838</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>Payments represent dividends being paid as permitted by North Carolina law.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Quintiles Transnational Holdings Inc.</issuerName>
                <signatureName>John Goodacre</signatureName>
                <nameOfSigner>John Goodacre</nameOfSigner>
                <signatureTitle>Secretary</signatureTitle>
                <signatureDate>2009-12-21</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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