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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 q5JPRkbpHqWaOh8KfIF5yA==

<SEC-DOCUMENT>0001209191-09-049512.txt : 20091022
<SEC-HEADER>0001209191-09-049512.hdr.sgml : 20091022
<ACCEPTANCE-DATETIME>20091022164412
ACCESSION NUMBER:		0001209191-09-049512
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091022
DATE AS OF CHANGE:		20091022
EFFECTIVENESS DATE:		20091022

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Unilife Medical Solutions Ltd
		CENTRAL INDEX KEY:			0001474891
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			C3

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-135535
		FILM NUMBER:		091132856

	BUSINESS ADDRESS:	
		STREET 1:		633 LOWTHER ROAD
		CITY:			LEWISBERRY
		STATE:			PA
		ZIP:			17339
		BUSINESS PHONE:		717 938 9323

	MAIL ADDRESS:	
		STREET 1:		633 LOWTHER ROAD
		CITY:			LEWISBERRY
		STATE:			PA
		ZIP:			17339
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001474891</cik>
        <entityName>Unilife Medical Solutions Ltd</entityName>
        <issuerAddress>
            <street1>633 Lowther Road</street1>
            <city>Lewisberry</city>
            <stateOrCountry>PA</stateOrCountry>
            <zipCode>17339</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>717-938-9323</issuerPhoneNumber>
        <jurisdictionOfInc>AUSTRALIA</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>Musgrave Block Holdings Limited</previousName>
            <previousName>Unitract Limited</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
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    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Alan</firstName>
                <lastName>Shortall</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jim</firstName>
                <lastName>Bosnjak</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jeff</firstName>
                <lastName>Carter</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <lastName>Galle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Daniel</firstName>
                <lastName>Calvert</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Bernhard</firstName>
                <lastName>Opitz</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eugene</firstName>
                <lastName>Shortall</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <lastName>Iampietro</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stephen</firstName>
                <lastName>Allan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Cynthia</firstName>
                <lastName>Lighty</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>633 Lowther Road</street1>
                <city>Lewisberry</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>17339</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$5,000,001 - $25,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-10-07</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>250000</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Summer Street Research Partners</recipientName>
                <recipientCRDNumber>127142</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>1 Beacon Street</street1>
                    <street2>34th Floor</street2>
                    <city>Boston</city>
                    <stateOrCountry>MA</stateOrCountry>
                    <zipCode>02108</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
            <recipient>
                <recipientName>Olympus Securities, LLC</recipientName>
                <recipientCRDNumber>114050</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>170 Changebridge Road</street1>
                    <street2>Suite B1</street2>
                    <city>Montville</city>
                    <stateOrCountry>NJ</stateOrCountry>
                    <zipCode>07045</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>5328948</totalOfferingAmount>
            <totalAmountSold>5328948</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>8</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>286447</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse>The company also issued options to purchase ordinary shares, exercisable at AU$0.85 to Summer Street Research Partners and Olympus Securities LLC.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>true</authorizedRepresentative>
            <signature>
                <issuerName>Unilife Medical Solutions Limited</issuerName>
                <signatureName>Alan Shortall</signatureName>
                <nameOfSigner>Alan Shortall</nameOfSigner>
                <signatureTitle>Chief Executive Officer and Director</signatureTitle>
                <signatureDate>2009-10-22</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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