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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001354358-10-000004.txt : 20100305
<SEC-HEADER>0001354358-10-000004.hdr.sgml : 20100305
<ACCEPTANCE-DATETIME>20100304203225
ACCESSION NUMBER:		0001354358-10-000004
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(7)
FILED AS OF DATE:		20100305
DATE AS OF CHANGE:		20100304
EFFECTIVENESS DATE:		20100305

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CTA Choice DRX
		CENTRAL INDEX KEY:			0001468322
		IRS NUMBER:				270302069
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-132715
		FILM NUMBER:		10658846

	BUSINESS ADDRESS:	
		STREET 1:		C/O CLARITY MANAGED ACCOUNT PLATFORM LLC
		STREET 2:		900 KING STREET, SUITE 100
		CITY:			RYE BROOK
		STATE:			NY
		ZIP:			10573
		BUSINESS PHONE:		914-307-7000

	MAIL ADDRESS:	
		STREET 1:		C/O CLARITY MANAGED ACCOUNT PLATFORM LLC
		STREET 2:		900 KING STREET, SUITE 100
		CITY:			RYE BROOK
		STATE:			NY
		ZIP:			10573
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001468322</cik>
        <entityName>CTA Choice DRX</entityName>
        <issuerAddress>
            <street1>900 KING STREET</street1>
            <street2>SUITE 100</street2>
            <city>RYE BROOK</city>
            <stateOrCountry>NY</stateOrCountry>
            <zipCode>10573</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>914-307-7000</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Kenneth</firstName>
                <middleName>Andrew</middleName>
                <lastName>Shewer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>900 King Street</street1>
                <street2>Suite 100</street2>
                <city>Rye Brook</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10573</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chairman and Co-Chief Executive Officer of ClariTy Managed Account &amp; Analytics Platform LLC, Issuer's Managing Member</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Marc</firstName>
                <middleName>Steven</middleName>
                <lastName>Goodman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>900 King Street</street1>
                <street2>Suite 100</street2>
                <city>Rye Brook</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10573</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>President and Co-Chief Executive Officer of ClariTy Managed Account &amp; Analytics Platform LLC, Issuer's Managing Member</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Esther</firstName>
                <middleName>Eckerling</middleName>
                <lastName>Goodman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>900 King Street</street1>
                <street2>Suite 100</street2>
                <city>Rye Brook</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10573</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Senior Executive Vice President and Chief Operating Officer of ClariTy Managed Account &amp; Analytics Platform LLC, Issuer's Managing Member</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Lawrence</firstName>
                <middleName>Steven</middleName>
                <lastName>Block</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>900 King Street</street1>
                <street2>Suite 100</street2>
                <city>Rye Brook</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10573</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Vice President and General Counsel of ClariTy Managed Account &amp; Analytics Platform LLC, Issuer's Managing Member</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Maureen</firstName>
                <middleName>Danielle</middleName>
                <lastName>Howley</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>900 King Street</street1>
                <street2>Suite 100</street2>
                <city>Rye Brook</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10573</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Senior Vice President and Chief Financial Officer of ClariTy Managed Account &amp; Analytics Platform LLC, Issuer's Managing Member</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>$25,000,001 - $50,000,000</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.7</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001468322-09-000001</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-07-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>1000000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>49890274</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>5</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>CTA Choice DRX</issuerName>
                <signatureName>/s/ Lawrence S. Block</signatureName>
                <nameOfSigner>ClariTy Managed Account &amp; Analytics Platform LLC, its Managing Member, by Lawrence S. Block</nameOfSigner>
                <signatureTitle>EVP and General Counsel</signatureTitle>
                <signatureDate>2010-03-04</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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