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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001467910-10-000001.txt : 20100113
<SEC-HEADER>0001467910-10-000001.hdr.sgml : 20100113
<ACCEPTANCE-DATETIME>20100113154638
ACCESSION NUMBER:		0001467910-10-000001
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(1)
FILED AS OF DATE:		20100113
DATE AS OF CHANGE:		20100113
EFFECTIVENESS DATE:		20100113

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TARGETED TECHNOLOGY FUND I, LP
		CENTRAL INDEX KEY:			0001467910
		IRS NUMBER:				270479955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-132734
		FILM NUMBER:		10525132

	BUSINESS ADDRESS:	
		STREET 1:		12621 SILICON DRIVE
		STREET 2:		SUITE 100
		CITY:			SAN ANTONIO
		STATE:			TX
		ZIP:			78249
		BUSINESS PHONE:		210-340-0116

	MAIL ADDRESS:	
		STREET 1:		12621 SILICON DRIVE
		STREET 2:		SUITE 100
		CITY:			SAN ANTONIO
		STATE:			TX
		ZIP:			78249
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001467910</cik>
        <entityName>TARGETED TECHNOLOGY FUND I, LP</entityName>
        <issuerAddress>
            <street1>12621 SILICON DRIVE</street1>
            <street2>SUITE 100</street2>
            <city>SAN ANTONIO</city>
            <stateOrCountry>TX</stateOrCountry>
            <zipCode>78249</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>210-340-0116</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Limited Partnership</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>N/A</firstName>
                <middleName>N/A</middleName>
                <lastName>Incyte General Partner, LP</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>General Partner of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>N/A</firstName>
                <middleName>N/A</middleName>
                <lastName>Incyte Venture Partners LLC</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>General Partner of Incyte General Partner, LP</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <middleName>E.</middleName>
                <lastName>Banas</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Organizer of the Issuer and Manager of Incyte Venture Partners LLC</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Paul</firstName>
                <middleName>C.</middleName>
                <lastName>Castella</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Organizer of the Issuer and Manager of Incyte Venture Partners LLC</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Alan</firstName>
                <middleName>H.</middleName>
                <lastName>Dean</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Organizer of the Issuer and Manager of Incyte Venture Partners LLC</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Lukin</firstName>
                <middleName>T.</middleName>
                <lastName>Gilliland, Jr.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Organizer of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <middleName>F.</middleName>
                <lastName>Traa</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12621 Silicon Drive</street1>
                <street2>Suite 100</street2>
                <city>San Antonio</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>78249</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Organizer of the Issuer</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Venture Capital Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <revenueRange>No Revenues</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.1</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001467910-09-000005</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-06-30</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>10000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>50000000</totalOfferingAmount>
            <totalAmountSold>11235000</totalAmountSold>
            <totalRemaining>38765000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>48</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>2415525</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>Above is an estimate of the management fee to be paid to the general partner of the Issuer over the estimated 10 year term.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>TARGETED TECHNOLOGY FUND I, LP</issuerName>
                <signatureName>Paul C. Castella</signatureName>
                <nameOfSigner>Paul C. Castella</nameOfSigner>
                <signatureTitle>Manager of Incyte Venture Partners LLC</signatureTitle>
                <signatureDate>2010-01-13</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----