-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 BWfQKg+I6RxLuD2qUEUq0hu+aTzLo4bqmXrgeAdvpBUf9X92rT2tGnWuo7U0WBF5
 FyS9eogkNz+R5NYXN0jK9Q==

<SEC-DOCUMENT>0001463741-09-000003.txt : 20090908
<SEC-HEADER>0001463741-09-000003.hdr.sgml : 20090907
<ACCEPTANCE-DATETIME>20090904193232
ACCESSION NUMBER:		0001463741-09-000003
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090908
DATE AS OF CHANGE:		20090904
EFFECTIVENESS DATE:		20090908

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AVE MARIA BIOTECHNOLOGY, LLC
		CENTRAL INDEX KEY:			0001463741
		IRS NUMBER:				261839136
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-130799
		FILM NUMBER:		091056927

	BUSINESS ADDRESS:	
		STREET 1:		PO BOX 2248
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98111
		BUSINESS PHONE:		206-906-9922

	MAIL ADDRESS:	
		STREET 1:		PO BOX 2248
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98111
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0502</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001463741</cik>
        <entityName>AVE MARIA BIOTECHNOLOGY, LLC</entityName>
        <issuerAddress>
            <street1>1124 Columbia Street, Suite 650</street1>
            <street2></street2>
            <city>SEATTLE</city>
            <stateOrCountry>WA</stateOrCountry>
            <zipCode>98104</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>206-906-9922</issuerPhoneNumber>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <jurisdictionOfInc>WASHINGTON</jurisdictionOfInc>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Theresa</firstName>
                <middleName>A.</middleName>
                <lastName>Deisher</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1124 Columbia Street, Suite 650</street1>
                <street2>PO Box 2248</street2>
                <city>Seattle</city>
                <stateOrCountry>WA</stateOrCountry>
                <zipCode>98111</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Manager</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>No Revenues</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001463741-09-000002</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-09-04</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Convertible debt and warrants</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>25000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1000000</totalOfferingAmount>
            <totalAmountSold>225000</totalAmountSold>
            <totalRemaining>775000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>4</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>AVE MARIA BIOTECHNOLOGY, LLC</issuerName>
                <signatureName>/s/Theresa A. Deisher</signatureName>
                <nameOfSigner>Theresa A. Deisher</nameOfSigner>
                <signatureTitle>Manager</signatureTitle>
                <signatureDate>2009-09-04</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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