-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 TCYuz7z7Mb+nvpivps/imHqBd66KZG2Z76xFKbH9nrm6+EzKw0EO4lbPQz6/kaEk
 6xIjEn6URaJlH3F4SDke9A==

<SEC-DOCUMENT>0001463570-09-000002.txt : 20090810
<SEC-HEADER>0001463570-09-000002.hdr.sgml : 20090810
<ACCEPTANCE-DATETIME>20090810082426
ACCESSION NUMBER:		0001463570-09-000002
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090810
DATE AS OF CHANGE:		20090810
EFFECTIVENESS DATE:		20090810

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Palyon Medical Corp
		CENTRAL INDEX KEY:			0001463570
		IRS NUMBER:				061700008
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-130784
		FILM NUMBER:		09997556

	BUSINESS ADDRESS:	
		STREET 1:		250 W. 57TH STREET, SUITE 1716
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10107
		BUSINESS PHONE:		212-333-2050

	MAIL ADDRESS:	
		STREET 1:		250 W. 57TH STREET, SUITE 1716
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10107
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0502</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001463570</cik>
        <entityName>Palyon Medical Corp</entityName>
        <issuerAddress>
            <street1>250 W. 57TH STREET, SUITE 1716</street1>
            <street2></street2>
            <city>NEW YORK</city>
            <stateOrCountry>NY</stateOrCountry>
            <zipCode>10107</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>212-333-2050</issuerPhoneNumber>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2009</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName></middleName>
                <lastName>Present</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gregory</firstName>
                <middleName></middleName>
                <lastName>David</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Cherine</firstName>
                <middleName></middleName>
                <lastName>Plumaker</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <middleName></middleName>
                <lastName>Liang</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Daniel</firstName>
                <middleName></middleName>
                <lastName>Omstead</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Aidan</firstName>
                <middleName></middleName>
                <lastName>King</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Glen</firstName>
                <middleName></middleName>
                <lastName>Kashuba</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>250 West 57th Street</street1>
                <street2>Suite 1716</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10107</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001463570-09-000001</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-04-27</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Rockport Venture Securities, LLC</recipientName>
                <recipientCRDNumber>113748</recipientCRDNumber>
                <associatedBDName>Rockport Venture Securities, LLC</associatedBDName>
                <associatedBDCRDNumber>113748</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>275 Cabot Street</street1>
                    <street2>Suite 10</street2>
                    <city>Beverly</city>
                    <stateOrCountry>MA</stateOrCountry>
                    <zipCode>01915</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>IL</state>
                    <state>MA</state>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>24000000</totalOfferingAmount>
            <totalAmountSold>24000000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>11</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>1440000</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse>$1,260,000 was paid and a warrant to purchase 3,726,708 shares of common stock was issued in connection with the initial sale, and the balance was paid in cash after the sale of the remaining securities.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>47916</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>The issuer will use the proceeds for general corporate and working capital purposes, including the payment of salary to employees, including salary owed as of the date of the sale.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Palyon Medical Corp</issuerName>
                <signatureName>David Present</signatureName>
                <nameOfSigner>David Present</nameOfSigner>
                <signatureTitle>President</signatureTitle>
                <signatureDate>2009-08-07</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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