-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001456002-10-000001.txt : 20100319
<SEC-HEADER>0001456002-10-000001.hdr.sgml : 20100319
<ACCEPTANCE-DATETIME>20100319155840
ACCESSION NUMBER:		0001456002-10-000001
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 505
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100319
DATE AS OF CHANGE:		20100319
EFFECTIVENESS DATE:		20100319

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CLINICAL OUTCOMES MANAGEMENT SYSTEMS LLC
		CENTRAL INDEX KEY:			0001456002
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			OH

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-126876
		FILM NUMBER:		10694272

	BUSINESS ADDRESS:	
		STREET 1:		1801 EAST NINTH STREET
		STREET 2:		SUITE 1425
		CITY:			CLEVELAND
		STATE:			OH
		ZIP:			44114
		BUSINESS PHONE:		216-523-1962

	MAIL ADDRESS:	
		STREET 1:		1801 EAST NINTH STREET
		STREET 2:		SUITE 1425
		CITY:			CLEVELAND
		STATE:			OH
		ZIP:			44114
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001456002</cik>
        <entityName>CLINICAL OUTCOMES MANAGEMENT SYSTEMS LLC</entityName>
        <issuerAddress>
            <street1>1801 EAST NINTH STREET</street1>
            <street2>SUITE 1425</street2>
            <city>CLEVELAND</city>
            <stateOrCountry>OH</stateOrCountry>
            <zipCode>44114</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>216-523-1962</issuerPhoneNumber>
        <jurisdictionOfInc>OHIO</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Paul</firstName>
                <middleName>Hunter</middleName>
                <lastName>Carleton</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1801 East Ninth Street</street1>
                <street2>Suite 1425</street2>
                <city>Cleveland</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44114</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <middleName>James</middleName>
                <lastName>McKenna</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1801 East Ninth Street</street1>
                <street2>Suite 1425</street2>
                <city>Cleveland</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44114</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <middleName>Joseph</middleName>
                <lastName>Riemenschneider</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>652 Glen Eden Court</street1>
                <city>Aurora</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44202</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <middleName>Albert</middleName>
                <lastName>Riemenschneider</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>8544 Tanglewood Trail</street1>
                <city>Chagrin Falls</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44023</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Donna</firstName>
                <middleName>Zapis</middleName>
                <lastName>Thomas</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22900 Center Ridge Road</street1>
                <city>Rocky River</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44116</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Edward</firstName>
                <middleName>J.</middleName>
                <lastName>Tromczynksi</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>60 W. Streetsboro Street</street1>
                <street2>Suite 5</street2>
                <city>Hudson</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44236</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>F</middleName>
                <lastName>Zak</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>7690 Darbys Run</street1>
                <city>Chagrin Falls</city>
                <stateOrCountry>OH</stateOrCountry>
                <zipCode>44023</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Technology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$1 - $1,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>05</item>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001456002-09-000002</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2008-12-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>2750</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>3900500</totalOfferingAmount>
            <totalAmountSold>1700500</totalAmountSold>
            <totalRemaining>2200000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>16</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>200000</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>CLINICAL OUTCOMES MANAGEMENT SYSTEMS LLC</issuerName>
                <signatureName>/william c. mull/</signatureName>
                <nameOfSigner>William C. Mull</nameOfSigner>
                <signatureTitle>Attorney</signatureTitle>
                <signatureDate>2010-03-19</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----