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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 KWY3eE0ufaYb3X1r5XRbvg==

<SEC-DOCUMENT>0001448053-10-000002.txt : 20100204
<SEC-HEADER>0001448053-10-000002.hdr.sgml : 20100204
<ACCEPTANCE-DATETIME>20100204133309
ACCESSION NUMBER:		0001448053-10-000002
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100204
DATE AS OF CHANGE:		20100204
EFFECTIVENESS DATE:		20100204

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MOLECULAR BIOMETRICS INC
		CENTRAL INDEX KEY:			0001448053
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-123566
		FILM NUMBER:		10573485

	BUSINESS ADDRESS:	
		STREET 1:		SUITE 110, ONE EDGEWATER DRIVE
		CITY:			NORWOOD
		STATE:			MA
		ZIP:			02062
		BUSINESS PHONE:		781-501-5600

	MAIL ADDRESS:	
		STREET 1:		SUITE 110, ONE EDGEWATER DRIVE
		CITY:			NORWOOD
		STATE:			MA
		ZIP:			02062
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001448053</cik>
        <entityName>MOLECULAR BIOMETRICS INC</entityName>
        <issuerAddress>
            <street1>SUITE 110, ONE EDGEWATER DRIVE</street1>
            <city>NORWOOD</city>
            <stateOrCountry>MA</stateOrCountry>
            <zipCode>02062</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>781-501-5600</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
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        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <lastName>Posillico</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Molecular Biometrics, Inc.</street1>
                <street2>One Edgewater Drive, Suite 110</street2>
                <city>Norwood</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02062</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Bruce</firstName>
                <lastName>Goldstein</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Molecular Biometrics, Inc.</street1>
                <street2>One Edgewater Drive, Suite 110</street2>
                <city>Norwood</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02062</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Frank</firstName>
                <lastName>Thomas</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Molecular Biometrics, Inc.</street1>
                <street2>One Edgewater Drive, Suite 110</street2>
                <city>Norwood</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02062</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <lastName>Rochelle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Molecular Biometrics, Inc.</street1>
                <street2>One Edgewater Drive, Suite 110</street2>
                <city>Norwood</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02062</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <lastName>Datin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Safeguard Scientifics</street1>
                <street2>435 Devon Park Drive, Building 800</street2>
                <city>Wayne</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19087</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jonathan</firstName>
                <lastName>Fleming</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Oxford Bioscience Partners</street1>
                <street2>222 Berkeley Street, Suite 1650</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02116</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <lastName>Barrett</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Atlas Venture Fund VIII, L.P.</street1>
                <street2>320 Winter Street, Suite 320</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02476</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Edward</firstName>
                <lastName>Erickson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>6887 Tohickon Hill Road</street1>
                <city>Pipersville</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>18947</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>9999999997-08-042942</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-12-30</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>2</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>16961567</totalOfferingAmount>
            <totalAmountSold>12755376</totalAmountSold>
            <totalRemaining>4206191</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>16</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>2500000</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MOLECULAR BIOMETRICS INC</issuerName>
                <signatureName>/s/ Frank E. Thomas</signatureName>
                <nameOfSigner>Frank E. Thomas</nameOfSigner>
                <signatureTitle>Senior Vice President, Chief Operating Officer and Treasurer</signatureTitle>
                <signatureDate>2010-02-04</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----