-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 UEggIGodv82GU3kTjlqHVJXheuKRlsT1752P48pmONQqfmkMWWKU9bkF+GqtPBzj
 xYto3IZi7KUBcPvDF9U52g==

<SEC-DOCUMENT>0001140361-11-002157.txt : 20110110
<SEC-HEADER>0001140361-11-002157.hdr.sgml : 20110110
<ACCEPTANCE-DATETIME>20110110152331
ACCESSION NUMBER:		0001140361-11-002157
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20110110
DATE AS OF CHANGE:		20110110
EFFECTIVENESS DATE:		20110110

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NexGen Medical Systems Inc
		CENTRAL INDEX KEY:			0001440574
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-153330
		FILM NUMBER:		11520065

	BUSINESS ADDRESS:	
		STREET 1:		10471 double r blvd
		STREET 2:		SUITE A
		CITY:			Reno
		STATE:			NV
		ZIP:			89521
		BUSINESS PHONE:		775-851-7337

	MAIL ADDRESS:	
		STREET 1:		10471 double r blvd
		STREET 2:		SUITE A
		CITY:			Reno
		STATE:			NV
		ZIP:			89521
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001440574</cik>
        <entityName>NexGen Medical Systems Inc</entityName>
        <issuerAddress>
            <street1>10471 DOUBLE R BLVD.</street1>
            <street2>SUITE A</street2>
            <city>RENO</city>
            <stateOrCountry>NV</stateOrCountry>
            <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
            <zipCode>89521</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>775-851-7337</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Kucharczyk</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>10471 Double R. Blvd., Suite A</street1>
                <city>Reno</city>
                <stateOrCountry>NV</stateOrCountry>
                <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
                <zipCode>89521</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Rudy</firstName>
                <lastName>Mazzocchi</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>John Kucharczyk</street1>
                <city>Reno</city>
                <stateOrCountry>NV</stateOrCountry>
                <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
                <zipCode>89521</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <lastName>Latchaw</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>John Kucharczyk</street1>
                <city>Reno</city>
                <stateOrCountry>NV</stateOrCountry>
                <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
                <zipCode>89521</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Cary</firstName>
                <lastName>Adams</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>John Kucharczyk</street1>
                <city>Reno</city>
                <stateOrCountry>NV</stateOrCountry>
                <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
                <zipCode>89521</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joel</firstName>
                <lastName>Braunstein</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>18 Bellchase Court</street1>
                <city>Pikesville</city>
                <stateOrCountry>MD</stateOrCountry>
                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>21208</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Matthew</firstName>
                <lastName>Solar</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>10471 Double R. Blvd., Suite A</street1>
                <city>Reno</city>
                <stateOrCountry>NV</stateOrCountry>
                <stateOrCountryDescription>NEVADA</stateOrCountryDescription>
                <zipCode>89521</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>No Revenues</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-12-27</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Promissory note, underlying warrants and securities</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1500000</totalOfferingAmount>
            <totalAmountSold>690000</totalAmountSold>
            <totalRemaining>810000</totalRemaining>
            <clarificationOfResponse>(c) represents amount remaining to be sold, along with the potential exercise price of warrants issued pursuant to offering, each warrant share may be exercised for $2.00, which is adjustable pursuant to note and warrant purchase agreement.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>2</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>NexGen Medical Systems Inc</issuerName>
                <signatureName>/s/ John Kucharczyk</signatureName>
                <nameOfSigner>John Kucharczyk</nameOfSigner>
                <signatureTitle>President and Chief Executive Officer</signatureTitle>
                <signatureDate>2011-01-07</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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