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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001439210-10-000017.txt : 20100708
<SEC-HEADER>0001439210-10-000017.hdr.sgml : 20100708
<ACCEPTANCE-DATETIME>20100707191545
ACCESSION NUMBER:		0001439210-10-000017
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100708
DATE AS OF CHANGE:		20100707
EFFECTIVENESS DATE:		20100708

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AutoGenomics, Inc.
		CENTRAL INDEX KEY:			0001439210
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				043440258
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-143088
		FILM NUMBER:		10942896

	BUSINESS ADDRESS:	
		STREET 1:		2980 SCOTT STREET
		CITY:			VISTA
		STATE:			CA
		ZIP:			92081
		BUSINESS PHONE:		(760) 477-2248

	MAIL ADDRESS:	
		STREET 1:		2980 SCOTT STREET
		CITY:			VISTA
		STATE:			CA
		ZIP:			92081
</SEC-HEADER>
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<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
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        <entityName>AutoGenomics, Inc.</entityName>
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            <city>VISTA</city>
            <stateOrCountry>CA</stateOrCountry>
            <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
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                <lastName>Dattagupta, Ph.D.</lastName>
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                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92081</zipCode>
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                <firstName>Shailendra</firstName>
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        <relatedPersonInfo>
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                <firstName>Thomas</firstName>
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                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001439210-10-000008</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2006-05-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
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        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>25000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>18867294</totalOfferingAmount>
            <totalAmountSold>17632595</totalAmountSold>
            <totalRemaining>1234699</totalRemaining>
            <clarificationOfResponse>Offering consists of 6,399,635 shares of Series C Cov. Pref. Stock at $2.75 per share and warrants to purchase 444,363 shares of Series C Cov. Pref. Stock at an average exercise price of $2.86 per share. A total of 11,453 warrants have been exercised.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>67</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
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            </salesCommissions>
            <findersFees>
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            <clarificationOfResponse></clarificationOfResponse>
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        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
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            <signature>
                <issuerName>AutoGenomics, Inc.</issuerName>
                <signatureName>Thomas V. Hennessey, Jr.</signatureName>
                <nameOfSigner>Thomas V. Hennessey, Jr.</nameOfSigner>
                <signatureTitle>Chief Operating Officer and Chief Financial Officer</signatureTitle>
                <signatureDate>2010-07-07</signatureDate>
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