-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 EF7zNOiM31iI71reQTepRjZ/7S7kMUfoRSiZsYUDyvemhDsQQkC0XjrUDqcZNfIE
 wbNUBbzQs4Zz4FVADcSRbA==

<SEC-DOCUMENT>0001439210-10-000004.txt : 20100325
<SEC-HEADER>0001439210-10-000004.hdr.sgml : 20100325
<ACCEPTANCE-DATETIME>20100325153456
ACCESSION NUMBER:		0001439210-10-000004
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100325
DATE AS OF CHANGE:		20100325
EFFECTIVENESS DATE:		20100325

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AutoGenomics, Inc.
		CENTRAL INDEX KEY:			0001439210
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				043440258
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-139924
		FILM NUMBER:		10704529

	BUSINESS ADDRESS:	
		STREET 1:		2980 SCOTT STREET
		CITY:			VISTA
		STATE:			CA
		ZIP:			92801
		BUSINESS PHONE:		(760) 477-2248

	MAIL ADDRESS:	
		STREET 1:		2980 SCOTT STREET
		CITY:			VISTA
		STATE:			CA
		ZIP:			92801
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001439210</cik>
        <entityName>AutoGenomics, Inc.</entityName>
        <issuerAddress>
            <street1>2980 SCOTT STREET</street1>
            <city>VISTA</city>
            <stateOrCountry>CA</stateOrCountry>
            <zipCode>92801</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(760) 477-2248</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Nanibhushan</firstName>
                <lastName>Dattagupta, Ph.D.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Shailendra</firstName>
                <lastName>Singh, Ph.D.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ramanath</firstName>
                <lastName>Vairavan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Fareed</firstName>
                <lastName>Kureshy</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Laurence</firstName>
                <middleName>M.</middleName>
                <lastName>Demers</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eric</firstName>
                <middleName>S.</middleName>
                <lastName>Kentor</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <middleName>H.</middleName>
                <lastName>Davidson, D.B.A.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Randall</firstName>
                <middleName>R.</middleName>
                <lastName>Lunn</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName>P.</middleName>
                <lastName>Sullivan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <middleName>R.</middleName>
                <lastName>Testman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eugene</firstName>
                <middleName>J.</middleName>
                <lastName>Zurlo</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2980 Scott Street</street1>
                <city>Vista</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>92801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001439210-10-000002</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-03-09</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>125000</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Jefferies &amp; Company, Inc.</recipientName>
                <recipientCRDNumber>2347</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>520 Madison Avenue</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>AL</state>
                    <state>CA</state>
                    <state>CT</state>
                    <state>FL</state>
                    <state>GA</state>
                    <state>MD</state>
                    <state>MA</state>
                    <state>NV</state>
                    <state>TN</state>
                    <state>TX</state>
                    <state>VA</state>
                    <state>WV</state>
                    <state>WY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>13125000</totalOfferingAmount>
            <totalAmountSold>13125000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>Total offering amount is comprised of $5,250,000 of subordinated promissory notes and $7,875,000 of Warrants. The Company issued Warrants to purchase 1,575,000 shares of Common Stock at an exercise price of $5.00 per share (subject to adjustment ...</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>18</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>400000</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>AutoGenomics, Inc.</issuerName>
                <signatureName>Thomas V. Hennessey, Jr.</signatureName>
                <nameOfSigner>Thomas V. Hennessey, Jr.</nameOfSigner>
                <signatureTitle>Chief Operating Officer and Chief Financial Officer</signatureTitle>
                <signatureDate>2010-03-25</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----