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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 NLqh3aUed3165YHQLEPwoQ==

<SEC-DOCUMENT>0000898432-10-000405.txt : 20100319
<SEC-HEADER>0000898432-10-000405.hdr.sgml : 20100319
<ACCEPTANCE-DATETIME>20100319153208
ACCESSION NUMBER:		0000898432-10-000405
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100319
DATE AS OF CHANGE:		20100319
EFFECTIVENESS DATE:		20100319

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Wells Fargo Multi-Strategy 100 TEI Fund I, LLC
		CENTRAL INDEX KEY:			0001439167
		IRS NUMBER:				262902044
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-121774
		FILM NUMBER:		10694143

	BUSINESS ADDRESS:	
		STREET 1:		333 MARKET STREET
		STREET 2:		29TH FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94105
		BUSINESS PHONE:		415-371-3059

	MAIL ADDRESS:	
		STREET 1:		333 MARKET STREET
		STREET 2:		29TH FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94105
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001439167</cik>
        <entityName>Wells Fargo Multi-Strategy 100 TEI Fund I, LLC</entityName>
        <issuerAddress>
            <street1>333 MARKET STREET</street1>
            <street2>29TH FLOOR</street2>
            <city>SAN FRANCISCO</city>
            <stateOrCountry>CA</stateOrCountry>
            <zipCode>94105</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>415-371-3059</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Daniel</firstName>
                <middleName>J.</middleName>
                <lastName>Rauchle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Wells Fargo Alt. Asset Mgmt., LLC</street1>
                <street2>333 Market Street, 29th Floor</street2>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94105</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Officer of Wells Fargo Alternative Asset Management, LLC, Managing Member of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>N/A</firstName>
                <lastName>Wells Fargo Alternative Asset Management, LLC</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>333 Market Street, 29th Floor</street1>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94105</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eileen</firstName>
                <lastName>Alden</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Wells Fargo Alt. Asset Mgmt., LLC</street1>
                <street2>333 Market Street, 29th Floor</street2>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94105</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Officer of Wells Fargo Alternative Asset Management, LLC, Managing Member of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Doretta</firstName>
                <middleName>L.</middleName>
                <lastName>Dunegan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Wells Fargo Alt. Asset Mgmt., LLC</street1>
                <street2>333 Market Street, 29th Floor</street2>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94105</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Officer of Wells Fargo Alternative Asset Management, LLC, Managing Member of the Issuer</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>9999999997-08-036871</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2008-08-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>35225041</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>152</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Wells Fargo Multi-Strategy 100 TEI Fund I, LLC</issuerName>
                <signatureName>/s/ Daniel J. Rauchle</signatureName>
                <nameOfSigner>Daniel J. Rauchle, President of Wells Fargo Alternative Asset Management, LLC,</nameOfSigner>
                <signatureTitle>Managing Member of the Issuer</signatureTitle>
                <signatureDate>2010-03-11</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----