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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001417926-09-000005.txt : 20091014
<SEC-HEADER>0001417926-09-000005.hdr.sgml : 20091014
<ACCEPTANCE-DATETIME>20091014163907
ACCESSION NUMBER:		0001417926-09-000005
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091014
DATE AS OF CHANGE:		20091014
EFFECTIVENESS DATE:		20091014

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INVO Bioscience, Inc.
		CENTRAL INDEX KEY:			0001417926
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				204036208
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-135294
		FILM NUMBER:		091119497

	BUSINESS ADDRESS:	
		STREET 1:		100 CUMMINGS CENTER
		STREET 2:		SUITE 421E
		CITY:			BEVERLY
		STATE:			MA
		ZIP:			01915
		BUSINESS PHONE:		(978) 787-9505

	MAIL ADDRESS:	
		STREET 1:		100 CUMMINGS CENTER
		STREET 2:		SUITE 421E
		CITY:			BEVERLY
		STATE:			MA
		ZIP:			01915

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMY'S SALSA AJI DISTRIBUTION COMPANY, INC.
		DATE OF NAME CHANGE:	20071108
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001417926</cik>
        <entityName>INVO Bioscience, Inc.</entityName>
        <issuerAddress>
            <street1>100 CUMMINGS CENTER</street1>
            <street2>SUITE 421E</street2>
            <city>BEVERLY</city>
            <stateOrCountry>MA</stateOrCountry>
            <zipCode>01915</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(978) 787-9505</issuerPhoneNumber>
        <jurisdictionOfInc>NEVADA</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>EMY'S SALSA AJI DISTRIBUTION COMPANY, INC.</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>J.</middleName>
                <lastName>Bowdring</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>100 Cummings Center</street1>
                <street2>Suite 421E</street2>
                <city>Beverly</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01915</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Financial Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Kathleen</firstName>
                <lastName>Karloff</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>100 Cummings Center</street1>
                <street2>Suite 421E</street2>
                <city>Beverly</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01915</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Executive Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Claude</firstName>
                <lastName>Ranoux</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>100 Cummings Center</street1>
                <street2>Suite 421E</street2>
                <city>Beverly</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01915</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>President</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$1 - $1,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-07-14</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>7500</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Hallmark Investments, Inc.</recipientName>
                <recipientCRDNumber>135003</recipientCRDNumber>
                <associatedBDName>Edward Taylor</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>420 Lexington Avenue</street1>
                    <street2>8th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10170</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CO</state>
                    <state>GA</state>
                    <state>MA</state>
                    <state>MN</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>545000</totalOfferingAmount>
            <totalAmountSold>545000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>The issuer originally sought $500,000 but received $545,000.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>12</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>30000</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse>$30,000 paid to Hallmark Investments, Inc. plus $15,000 for legal/administrative fees.  Hallmark Investments, Inc. also received a warrant to purchase 300,000 shares at $0.10 per share.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>94350</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>This amount represents reimbursement for prior expenses.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>INVO Bioscience, Inc.</issuerName>
                <signatureName>/s/ Robert J. Bowdring</signatureName>
                <nameOfSigner>Robert J. Bowdring</nameOfSigner>
                <signatureTitle>Chief Financial Officer</signatureTitle>
                <signatureDate>2009-10-14</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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