-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 q+JHxIcEZfqyrlPXseFmrg==

<SEC-DOCUMENT>0001192482-09-000095.txt : 20090413
<SEC-HEADER>0001192482-09-000095.hdr.sgml : 20090413
<ACCEPTANCE-DATETIME>20090413150926
ACCESSION NUMBER:		0001192482-09-000095
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090413
DATE AS OF CHANGE:		20090413
EFFECTIVENESS DATE:		20090413

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Diasome Pharmaceuticals LLC
		CENTRAL INDEX KEY:			0001411617
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			PA

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-108333
		FILM NUMBER:		09746508

	BUSINESS ADDRESS:	
		STREET 1:		625 Ridge Pike
		STREET 2:		Suite E-402
		CITY:			Conshohocken
		STATE:			PA
		ZIP:			19428

	MAIL ADDRESS:	
		STREET 1:		625 Ridge Pike
		STREET 2:		Suite E-402
		CITY:			Conshohocken
		STATE:			PA
		ZIP:			19428
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0301</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001411617</cik>
        <entityName>Diasome Pharmaceuticals LLC</entityName>
        <issuerAddress>
            <street1>625 Ridge Pike</street1>
            <street2>Suite 402</street2>
            <city>Conshohocken</city>
            <stateOrCountry>PA</stateOrCountry>
            <zipCode>19428</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>610.923.9443</issuerPhoneNumber>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <jurisdictionOfInc>PA</jurisdictionOfInc>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2008</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Len</firstName>
                <middleName></middleName>
                <lastName>Rosenberg</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>625 Ridge Pike, Suite 402</street1>
                <street2></street2>
                <city>Conshohocken</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19428</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName></middleName>
                <lastName>Geho</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>625 Ridge Pike, Suite 402</street1>
                <street2></street2>
                <city>Conshohocken</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19428</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>W.</firstName>
                <middleName>Blair</middleName>
                <lastName>Geho</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>625 Ridge Pike, Suite 402</street1>
                <street2></street2>
                <city>Conshohocken</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19428</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Brenda</firstName>
                <middleName></middleName>
                <lastName>Gavin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Quaker Bioventures</street1>
                <street2>Cira Center, 2929 Arch Street</street2>
                <city>Philadelphia</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19104</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Devang</firstName>
                <middleName></middleName>
                <lastName>Kantesaria</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1400 Liberty Ridge Drive, Suite 103</street1>
                <street2></street2>
                <city>Wayne</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19087</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName></middleName>
                <lastName>Caruso</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Provco Group</street1>
                <street2>795 E. Lancaster Avenue, Suite 200</street2>
                <city>Villanova</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19085</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>9999999997-08-021146</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2008-03-27</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isDebtType>true</isDebtType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>13752</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>13400000</totalOfferingAmount>
            <totalAmountSold>12900000</totalAmountSold>
            <totalRemaining>500000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>9</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Diasome Pharmaceuticals LLC</issuerName>
                <signatureName>Len Rosenberg</signatureName>
                <nameOfSigner>Len Rosenberg</nameOfSigner>
                <signatureTitle>President</signatureTitle>
                <signatureDate>2009-04-10</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----