-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 O9tfjO6cJ32vRWA4+aJ2BntZmYaA8hJGaUG3yU4rG39m8pXRma91gA8CI1ircvP9
 jAT8Qz/FDwiq3K0srERHxA==

<SEC-DOCUMENT>0001393434-09-000005.txt : 20090701
<SEC-HEADER>0001393434-09-000005.hdr.sgml : 20090701
<ACCEPTANCE-DATETIME>20090701170748
ACCESSION NUMBER:		0001393434-09-000005
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090701
DATE AS OF CHANGE:		20090701
EFFECTIVENESS DATE:		20090701

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			I-THERAPEUTIX INC
		CENTRAL INDEX KEY:			0001393434
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-101055
		FILM NUMBER:		09923288

	BUSINESS ADDRESS:	
		STREET 1:		235 BEAR HILL RD SUITE 301
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
		BUSINESS PHONE:		781-895-3235

	MAIL ADDRESS:	
		STREET 1:		235 BEAR HILL RD SUITE 301
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0401</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001393434</cik>
        <entityName>I-THERAPEUTIX INC</entityName>
        <issuerAddress>
            <street1>235 BEAR HILL RD SUITE 301</street1>
            <street2></street2>
            <city>WALTHAM</city>
            <stateOrCountry>MA</stateOrCountry>
            <zipCode>02451</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>781-895-3235</issuerPhoneNumber>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2006</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Amarpreet</firstName>
                <middleName></middleName>
                <lastName>Sawhney</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>235 Bear Hill Road</street1>
                <street2>Suite 301</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Farhad</firstName>
                <middleName></middleName>
                <lastName>Khosravi</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>235 Bear Hill Road</street1>
                <street2>Suite 301</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <middleName></middleName>
                <lastName>Cagnetta</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>235 Bear Hill Road</street1>
                <street2>Suite 301</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Samuel</firstName>
                <middleName></middleName>
                <lastName>Wu</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>235 Bear Hill Road</street1>
                <street2>Suite 301</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Charles</firstName>
                <middleName></middleName>
                <lastName>Warden</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>235 Bear Hill Road</street1>
                <street2>Suite 301</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>9999999997-07-012313</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2006-10-30</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>1000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1145836</totalOfferingAmount>
            <totalAmountSold>1145836</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>18</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>I-THERAPEUTIX INC</issuerName>
                <signatureName>Steven J. Cagnetta</signatureName>
                <nameOfSigner>Steven J. Cagnetta</nameOfSigner>
                <signatureTitle>Secretary</signatureTitle>
                <signatureDate>2009-07-01</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----