-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 R7G1R3mWTcsMLBCW22gT4YPxZRkEEmDL8upeVMiUqUMAFsVtXbsu9WJnkvQGbT/X
 MyP1sX7a1TDmxJiwzx6Btg==

<SEC-DOCUMENT>0001140361-10-001692.txt : 20100113
<SEC-HEADER>0001140361-10-001692.hdr.sgml : 20100113
<ACCEPTANCE-DATETIME>20100113134122
ACCESSION NUMBER:		0001140361-10-001692
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100113
DATE AS OF CHANGE:		20100113
EFFECTIVENESS DATE:		20100113

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MEDVENTIVE INC
		CENTRAL INDEX KEY:			0001376460
		IRS NUMBER:				205537609
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-95043
		FILM NUMBER:		10524691

	BUSINESS ADDRESS:	
		STREET 1:		400 FIFTH AVENUE
		STREET 2:		SUITE 200
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
		BUSINESS PHONE:		(781) 290-2500

	MAIL ADDRESS:	
		STREET 1:		400 FIFTH AVENUE
		STREET 2:		SUITE 200
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001376460</cik>
        <entityName>MEDVENTIVE INC</entityName>
        <issuerAddress>
            <street1>400 FIFTH AVENUE</street1>
            <street2>SUITE 200</street2>
            <city>WALTHAM</city>
            <stateOrCountry>MA</stateOrCountry>
            <zipCode>02451</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(781) 290-2500</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jonathan</firstName>
                <lastName>Niloff</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>400 Fifth Avenue</street1>
                <street2>Suite 200</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Nancy</firstName>
                <lastName>Ham</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>400 Fifth</street1>
                <street2>Suite 200</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <lastName>Gura</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o HLM Venture Partners Fund II, L.P.</street1>
                <street2>222 Berkeley Street, 21st Floor</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02116</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <lastName>Collins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>400 Fifth Avenue</street1>
                <street2>Suite 200</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Enrico</firstName>
                <lastName>Petrillo</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Prudential Tower</street1>
                <street2>800 Boylston Street  Suite 1585</street2>
                <city>Boston</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>02199</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <middleName>J.</middleName>
                <lastName>Levine</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Core Capital Partners</street1>
                <street2>1401 I Street, N.W., Suite 1000</street2>
                <city>Washington</city>
                <stateOrCountry>DC</stateOrCountry>
                <zipCode>20005</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0000929638-09-001192</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-06-29</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>25000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>9000000</totalOfferingAmount>
            <totalAmountSold>9000000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>8</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MEDVENTIVE INC</issuerName>
                <signatureName>/s/ Mark Collins</signatureName>
                <nameOfSigner>Mark Collins</nameOfSigner>
                <signatureTitle>Chief Financial Officer</signatureTitle>
                <signatureDate>2010-01-12</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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