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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 hVBT2cKZpjXQWf9pU9tZ1g==

<SEC-DOCUMENT>0001140361-10-045095.txt : 20101112
<SEC-HEADER>0001140361-10-045095.hdr.sgml : 20101111
<ACCEPTANCE-DATETIME>20101112115621
ACCESSION NUMBER:		0001140361-10-045095
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20101112
DATE AS OF CHANGE:		20101112
EFFECTIVENESS DATE:		20101112

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTREXON CORP
		CENTRAL INDEX KEY:			0001356090
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			VA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-87199
		FILM NUMBER:		101184507

	BUSINESS ADDRESS:	
		STREET 1:		1872 PRATT DRIVE
		STREET 2:		SUITE 1400
		CITY:			BLACKSBURG
		STATE:			VA
		ZIP:			24060
		BUSINESS PHONE:		301-556-9809

	MAIL ADDRESS:	
		STREET 1:		1872 PRATT DRIVE
		STREET 2:		SUITE 1400
		CITY:			BLACKSBURG
		STATE:			VA
		ZIP:			24060
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001356090</cik>
        <entityName>INTREXON CORP</entityName>
        <issuerAddress>
            <street1>1872 Pratt Drive</street1>
            <street2>Suite 1400</street2>
            <city>Blacksburg</city>
            <stateOrCountry>VA</stateOrCountry>
            <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
            <zipCode>24060</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>540-961-0725</issuerPhoneNumber>
        <jurisdictionOfInc>VIRGINIA</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>Genomatix Corporation</previousName>
            <previousName>Genomatix, Inc.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
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        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
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    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <lastName>Reed</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Sunil</firstName>
                <lastName>Chada</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Rick</firstName>
                <lastName>Sterling</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>P.</middleName>
                <lastName>Beech</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Randal</firstName>
                <middleName>J.</middleName>
                <lastName>Kirk</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ronald</firstName>
                <middleName>B.</middleName>
                <lastName>Herberman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Cesar</firstName>
                <middleName>L.</middleName>
                <lastName>Alvarez</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <lastName>Frank</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Larry</firstName>
                <lastName>Horner</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Dean</firstName>
                <middleName>J.</middleName>
                <lastName>Mitchell</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Burton</firstName>
                <lastName>Sobel</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Grace</firstName>
                <lastName>Colon</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Tom</firstName>
                <lastName>Goralski</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gerardo</firstName>
                <lastName>Zapata</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Intrexon Corporation</street1>
                <street2>1872 Pratt Drive, Suite 1400</street2>
                <city>Blacksburg</city>
                <stateOrCountry>VA</stateOrCountry>
                <stateOrCountryDescription>VIRGINIA</stateOrCountryDescription>
                <zipCode>24060</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001140361-10-010191</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-02-19</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Series D Preferred Shares, convertible into shares of common stock</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>37506714</totalOfferingAmount>
            <totalAmountSold>37506714</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>Amounts are rounded to nearest dollar</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>65</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>INTREXON CORP</issuerName>
                <signatureName>/s/ Rick Sterling</signatureName>
                <nameOfSigner>Rick Sterling</nameOfSigner>
                <signatureTitle>Chief Financial Officer</signatureTitle>
                <signatureDate>2010-11-10</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----