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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001393725-10-000086.txt : 20100224
<SEC-HEADER>0001393725-10-000086.hdr.sgml : 20100224
<ACCEPTANCE-DATETIME>20100224164115
ACCESSION NUMBER:		0001393725-10-000086
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(7)
FILED AS OF DATE:		20100224
DATE AS OF CHANGE:		20100224
EFFECTIVENESS DATE:		20100224

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MCDONNELL LOAN OPPORTUNITY FUND OFFSHORE, a class of the McDonnell Series Trust
		CENTRAL INDEX KEY:			0001356020
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-87105
		FILM NUMBER:		10630218

	BUSINESS ADDRESS:	
		STREET 1:		1515 W 22ND ST
		STREET 2:		11TH FL
		CITY:			OAK BROOK
		STATE:			IL
		ZIP:			60523
		BUSINESS PHONE:		630-684-8600

	MAIL ADDRESS:	
		STREET 1:		1515 W 22ND ST
		STREET 2:		11TH FL
		CITY:			OAK BROOK
		STATE:			IL
		ZIP:			60523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MCDONNELL LOAN OPPORTUNITY FUND OFFSHORE
		DATE OF NAME CHANGE:	20060313
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001356020</cik>
        <entityName>MCDONNELL LOAN OPPORTUNITY FUND OFFSHORE, a class of the McDonnell Series Trust</entityName>
        <issuerAddress>
            <street1>1515 W 22ND ST</street1>
            <street2>11TH FL</street2>
            <city>OAK BROOK</city>
            <stateOrCountry>IL</stateOrCountry>
            <zipCode>60523</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>630-684-8600</issuerPhoneNumber>
        <jurisdictionOfInc>CAYMAN ISLANDS</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>MCDONNELL LOAN OPPORTUNITY FUND OFFSHORE</previousName>
        </edgarPreviousNameList>
        <entityType>Other</entityType>
        <entityTypeOtherDesc>a Cayman Islands unit trust</entityTypeOtherDesc>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2005</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Kamradt</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1515 West 22nd Street</street1>
                <street2>11th Floor</street2>
                <city>Oak Brook</city>
                <stateOrCountry>IL</stateOrCountry>
                <zipCode>60523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Officer of McDonnell Investment Management, LLC, the Manager and Promoter of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>McCareins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1515 West 22nd Street</street1>
                <street2>11th Floor</street2>
                <city>Oak Brook</city>
                <stateOrCountry>IL</stateOrCountry>
                <zipCode>60523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Officer of McDonnell Investment Management, LLC, the Manager and Promoter of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Edward</firstName>
                <lastName>Treichel</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1515 West 22nd Street</street1>
                <street2>11th Floor</street2>
                <city>Oak Brook</city>
                <stateOrCountry>IL</stateOrCountry>
                <zipCode>60523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Officer of McDonnell Investment Management, LLC, the Manager and Promoter of the Issuer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Dennis</firstName>
                <lastName>McDonnell</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1515 West 22nd Street</street1>
                <street2>11th Floor</street2>
                <city>Oak Brook</city>
                <stateOrCountry>IL</stateOrCountry>
                <zipCode>60523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Executive Officer of McDonnell Investment Management, LLC, the Manager and Promoter of the Issuer</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.7</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001393725-09-000084</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2005-04-04</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Deutche Bank Securities Inc.</recipientName>
                <recipientCRDNumber>2525</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>60 Wall Street</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10005</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
            </recipient>
            <recipient>
                <recipientName>Western International Securities</recipientName>
                <recipientCRDNumber>39262</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>70 Lake Street</street1>
                    <street2>Suite 700</street2>
                    <city>Pasadena</city>
                    <stateOrCountry>CA</stateOrCountry>
                    <zipCode>91101</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
            </recipient>
            <recipient>
                <recipientName>BMO Capital Markets Corp.</recipientName>
                <recipientCRDNumber>16686</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>115 South LaSalle Street</street1>
                    <street2>13th Floor West</street2>
                    <city>Chicago</city>
                    <stateOrCountry>IL</stateOrCountry>
                    <zipCode>60603</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>127729978</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>81</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>2032295</dollarAmount>
                <isEstimate>true</isEstimate>
            </findersFees>
            <clarificationOfResponse>The Manager pays third party finders an agreed upon percentage of the management fees the Manager earns from investors referred by the finder.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>Customary advisory fees are paid by the Issuer Investment Manager as provided for in the Issuer's offering materials.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MCDONNELL LOAN OPPORTUNITY FUND OFFSHORE, a class of the McDonnell Series Trust</issuerName>
                <signatureName>/s/ Philip W. Cecil</signatureName>
                <nameOfSigner>Philip W. Cecil</nameOfSigner>
                <signatureTitle>General Counsel of the Investment Manager of the Issuer</signatureTitle>
                <signatureDate>2010-02-24</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----