-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 GznZfIjtn2yRX85NTguQV4rj61Ox9Wq6tSk70n2FFJeZE61ppxfbcCxi58nRmY70
 MVah3o7jKHPPeV8uhk18AQ==

<SEC-DOCUMENT>0001181431-10-038831.txt : 20100728
<SEC-HEADER>0001181431-10-038831.hdr.sgml : 20100728
<ACCEPTANCE-DATETIME>20100728145453
ACCESSION NUMBER:		0001181431-10-038831
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100728
DATE AS OF CHANGE:		20100728
EFFECTIVENESS DATE:		20100728

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ADVANCED ICU CARE, INC.
		CENTRAL INDEX KEY:			0001352029
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-145586
		FILM NUMBER:		10974125

	BUSINESS ADDRESS:	
		STREET 1:		999 EXECUTIVE OFFICE PARKWAY
		STREET 2:		SUITE 210
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63141
		BUSINESS PHONE:		314-514-6000

	MAIL ADDRESS:	
		STREET 1:		999 EXECUTIVE OFFICE PARKWAY
		STREET 2:		SUITE 210
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63141

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED ICU CARE INC
		DATE OF NAME CHANGE:	20060202
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001352029</cik>
        <entityName>ADVANCED ICU CARE, INC.</entityName>
        <issuerAddress>
            <street1>999 Executive Parkway, Suite 210</street1>
            <city>St. Louis</city>
            <stateOrCountry>MO</stateOrCountry>
            <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
            <zipCode>63141</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(314) 514-6000</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <previousName>ADVANCED ICU CARE INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2006</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mary</firstName>
                <middleName>Jo</middleName>
                <lastName>Gorman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName>N.</middleName>
                <lastName>Schopp</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Isabelle</firstName>
                <lastName>Kopec</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Barbara</firstName>
                <lastName>Lubash</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Mikolajczyk</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Tim</firstName>
                <lastName>Petersen</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>C.</firstName>
                <middleName>Thomas</middleName>
                <lastName>Smith</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Toby</firstName>
                <lastName>Thomas</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>999 Executive Parkway, Suite 210</street1>
                <city>St. Louis</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-07-16</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1001000</totalOfferingAmount>
            <totalAmountSold>500500</totalAmountSold>
            <totalRemaining>500500</totalRemaining>
            <clarificationOfResponse>Represents the sale of Secured Subordinated Convertible Promissory Notes in the aggregate principal amount of $500,000 and Warrants to purchase up to 483,871 shares of Common Stock at an exercise price of $0.31 per share.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>7</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>true</authorizedRepresentative>
            <signature>
                <issuerName>Advanced ICU Care, Inc.</issuerName>
                <signatureName>/s/ David N. Schopp</signatureName>
                <nameOfSigner>David N. Schopp</nameOfSigner>
                <signatureTitle>President</signatureTitle>
                <signatureDate>2010-07-28</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----