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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 Zpsk9hYx70EvGKHvQaaVzw==

<SEC-DOCUMENT>0001335480-09-000003.txt : 20091005
<SEC-HEADER>0001335480-09-000003.hdr.sgml : 20091005
<ACCEPTANCE-DATETIME>20091005113927
ACCESSION NUMBER:		0001335480-09-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091005
DATE AS OF CHANGE:		20091005
EFFECTIVENESS DATE:		20091005

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			XANODYNE PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0001335480
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-79890
		FILM NUMBER:		091104571

	BUSINESS ADDRESS:	
		STREET 1:		ONE RIVERFRONT PLACE
		CITY:			NEWPORT
		STATE:			KY
		ZIP:			41071
		BUSINESS PHONE:		8593717581

	MAIL ADDRESS:	
		STREET 1:		ONE RIVERFRONT PLACE
		CITY:			NEWPORT
		STATE:			KY
		ZIP:			41071
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
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            <city>NEWPORT</city>
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            <zipCode>41071</zipCode>
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                <stateOrCountry>KY</stateOrCountry>
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                <firstName>James</firstName>
                <lastName>Shannon</lastName>
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                <city>Newport</city>
                <stateOrCountry>KY</stateOrCountry>
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        <relatedPersonInfo>
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                <firstName>Thomas</firstName>
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                <firstName>Gary</firstName>
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                <city>Newport</city>
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                <zipCode>41071</zipCode>
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                <firstName>Peter</firstName>
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                <city>Newport</city>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Natasha</firstName>
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                <firstName>Rita</firstName>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
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            <dateOfFirstSale>
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        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
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        <typesOfSecuritiesOffered>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Stock Appreciation Rights</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>6022000</totalOfferingAmount>
            <totalAmountSold>0</totalAmountSold>
            <totalRemaining>6022000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>0</totalNumberAlreadyInvested>
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        <salesCommissionsFindersFees>
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                <issuerName>XANODYNE PHARMACEUTICALS INC</issuerName>
                <signatureName>/s/ Thomas P. Jennings</signatureName>
                <nameOfSigner>Thomas P. Jennings</nameOfSigner>
                <signatureTitle>Secretary</signatureTitle>
                <signatureDate>2009-10-05</signatureDate>
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