-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 AzK6T4Jw3IWShcvdY+G+3DTgvNHqSdROYZ3QQcDuxX3ERNcUOY+8PVvB2zKp9avz
 fJAkwW3wu2fXV9Gcy+DL2g==

<SEC-DOCUMENT>0001297931-10-000003.txt : 20100527
<SEC-HEADER>0001297931-10-000003.hdr.sgml : 20100527
<ACCEPTANCE-DATETIME>20100527093307
ACCESSION NUMBER:		0001297931-10-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100527
DATE AS OF CHANGE:		20100527
EFFECTIVENESS DATE:		20100527

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Icera Inc.
		CENTRAL INDEX KEY:			0001297931
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-142635
		FILM NUMBER:		10861069

	BUSINESS ADDRESS:	
		STREET 1:		2520 QUADRANT AZTEC WEST
		CITY:			BRISTOL
		STATE:			X0
		ZIP:			BS32 4AQ
		BUSINESS PHONE:		44145284800

	MAIL ADDRESS:	
		STREET 1:		2520 QUADRANT AZTEC WEST
		CITY:			BRISTOL
		STATE:			X0
		ZIP:			BS32 4AQ

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Icera Inc
		DATE OF NAME CHANGE:	20040721
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001297931</cik>
        <entityName>Icera Inc.</entityName>
        <issuerAddress>
            <street1>2520 THE QUADRANT, AZTEC WEST</street1>
            <city>BRISTOL</city>
            <stateOrCountry>X0</stateOrCountry>
            <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
            <zipCode>BS32 4AQ</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>44145284800</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>Comnios Inc.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <previousName>Icera Inc</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stan</firstName>
                <lastName>Boland</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Icera Inc.</street1>
                <street2>2520 The Quadrant, Aztec West</street2>
                <city>Bristol</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>BS32 4AQ</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Simon</firstName>
                <lastName>Knowles</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Icera Inc.</street1>
                <street2>2520 The Quadrant, Aztec West</street2>
                <city>Bristol</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>BS32 4AQ</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steve</firstName>
                <lastName>Chandler</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Icera Inc.</street1>
                <street2>2520 The Quadrant, Aztec West</street2>
                <city>Bristol</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>BS32 4AQ</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jon</firstName>
                <lastName>Oates</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Icera Inc.</street1>
                <street2>2520 The Quadrant, Aztec West</street2>
                <city>Bristol</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>BS32 4AQ</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Kevin</firstName>
                <lastName>Comolli</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Accel Partners</street1>
                <street2>16 St. James's Street</street2>
                <city>London</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>SQ1A 1ER</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <lastName>Evans</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Balderton Capital Partners</street1>
                <street2>20 Balderton Street</street2>
                <city>London</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>W1K 6TL</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Hermann</firstName>
                <lastName>Hauser</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Amadeus Capital</street1>
                <street2>Mount Pleasant House, 2 Mount Pleasant</street2>
                <city>Cambridge</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>CB3 0RN</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Graham</firstName>
                <lastName>O'Keeffe</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Atlas Venture Partners</street1>
                <street2>890 Winter Street, Suite 320</street2>
                <city>Waltham</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>02451</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Krishna</firstName>
                <lastName>Visvanathan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Esprit Nominees Limited</street1>
                <street2>14 Buckingham Gate</street2>
                <city>London</city>
                <stateOrCountry>X0</stateOrCountry>
                <stateOrCountryDescription>UNITED KINGDOM</stateOrCountryDescription>
                <zipCode>SW1 E6LB</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Technology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-05-21</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>46585500</totalOfferingAmount>
            <totalAmountSold>24560278</totalAmountSold>
            <totalRemaining>22025222</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>17</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Icera Inc.</issuerName>
                <signatureName>Stan Boland</signatureName>
                <nameOfSigner>Stan Boland</nameOfSigner>
                <signatureTitle>President</signatureTitle>
                <signatureDate>2010-05-24</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----