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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 hoPfboS4D6eeJkRYAsaeZQ==

<SEC-DOCUMENT>0001287098-09-000004.txt : 20091013
<SEC-HEADER>0001287098-09-000004.hdr.sgml : 20091012
<ACCEPTANCE-DATETIME>20091013131313
ACCESSION NUMBER:		0001287098-09-000004
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091013
DATE AS OF CHANGE:		20091013
EFFECTIVENESS DATE:		20091013

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MAXCYTE, INC.
		CENTRAL INDEX KEY:			0001287098
		IRS NUMBER:				522210438
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-64601
		FILM NUMBER:		091116238

	BUSINESS ADDRESS:	
		STREET 1:		22 FIRSTFIELD ROAD
		STREET 2:		SUITE 250
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878
		BUSINESS PHONE:		301-517-5556

	MAIL ADDRESS:	
		STREET 1:		22 FIRSTFIELD ROAD
		STREET 2:		SUITE 250
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MAXCYTE INC
		DATE OF NAME CHANGE:	20040415
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001287098</cik>
        <entityName>MAXCYTE, INC.</entityName>
        <issuerAddress>
            <street1>22 FIRSTFIELD ROAD</street1>
            <street2>SUITE 110</street2>
            <city>GAITHERSBURG</city>
            <stateOrCountry>MD</stateOrCountry>
            <zipCode>20878</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>301-944-1624</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>MAXCYTE INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Douglas</firstName>
                <middleName>A.</middleName>
                <lastName>Doerfler</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ronald</firstName>
                <middleName>E.</middleName>
                <lastName>Holtz</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Madhusadan</firstName>
                <lastName>Peshwa</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>J.</firstName>
                <middleName>Starke</middleName>
                <lastName>Thompson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <lastName>Pierson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Chris</firstName>
                <lastName>Hegele</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Will</firstName>
                <lastName>Brooke</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stan</firstName>
                <lastName>Erck</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Arthur</firstName>
                <lastName>Mandell</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Karen</firstName>
                <lastName>Donato</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Sinclair</firstName>
                <lastName>Dunlop</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>22 FIRSTFIELD ROAD</street1>
                <street2>Suite 110</street2>
                <city>GAITHERSBURG</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>20878</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001287098-09-000003</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-08-13</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isDebtType>true</isDebtType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1500000</totalOfferingAmount>
            <totalAmountSold>1500000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>15</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>excluding ordinary salary and expenses</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MAXCYTE, INC.</issuerName>
                <signatureName>Douglas A. Doerfler</signatureName>
                <nameOfSigner>Douglas A. Doerfler</nameOfSigner>
                <signatureTitle>President</signatureTitle>
                <signatureDate>2009-10-13</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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