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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 0PKV1N8Nh2yCxR2pMXdOzQ==

<SEC-DOCUMENT>0000919574-10-002571.txt : 20100316
<SEC-HEADER>0000919574-10-002571.hdr.sgml : 20100316
<ACCEPTANCE-DATETIME>20100316154709
ACCESSION NUMBER:		0000919574-10-002571
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
ITEM INFORMATION:		Investment Company Act Section 3(c)
ITEM INFORMATION:		Section 3(c)(1)
FILED AS OF DATE:		20100316
DATE AS OF CHANGE:		20100316
EFFECTIVENESS DATE:		20100316

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Amici Healthcare, L.P.
		CENTRAL INDEX KEY:			0001279829
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-62883
		FILM NUMBER:		10685482

	BUSINESS ADDRESS:	
		STREET 1:		C/O CF ADVISORS, LLC
		STREET 2:		666 FIFTH AVENUE, 34TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10103
		BUSINESS PHONE:		212-484-5000

	MAIL ADDRESS:	
		STREET 1:		C/O CF ADVISORS, LLC
		STREET 2:		666 FIFTH AVENUE, 34TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10103

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMICI HEALTHCARE L P
		DATE OF NAME CHANGE:	20040211
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001279829</cik>
        <entityName>Amici Healthcare, L.P.</entityName>
        <issuerAddress>
            <street1>c/o CF Advisors, LLC</street1>
            <street2>666 Fifth Avenue, 34th Floor</street2>
            <city>New York</city>
            <stateOrCountry>NY</stateOrCountry>
            <zipCode>10103</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>212-484-5000</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>AMICI HEALTHCARE L P</previousName>
        </edgarPreviousNameList>
        <entityType>Limited Partnership</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Alpheus</firstName>
                <middleName>A.</middleName>
                <lastName>Porter</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o CF Advisors, LLC</street1>
                <street2>666 Fifth Avenue, 34th Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10103</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Alpheus A. Porter is an executive officer of CF Advisors, LLC, the General Partner of the Issuer.</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Paul</firstName>
                <middleName>E.</middleName>
                <lastName>Orlin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o CF Advisors, LLC</street1>
                <street2>666 Fifth Avenue, 34th Floor</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10103</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Paul Orlin is an executive officer of CF Advisors, LLC, the General Partner of the Issuer.</relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.1</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0000919574-09-007912</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2004-01-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>1000000</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Christopher E. Engel</recipientName>
                <recipientCRDNumber>1495822</recipientCRDNumber>
                <associatedBDName>Sword Securities Corporation</associatedBDName>
                <associatedBDCRDNumber>32244</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>34 Chambers Street</street1>
                    <city>Princeton</city>
                    <stateOrCountry>NJ</stateOrCountry>
                    <zipCode>08540</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CA</state>
                    <state>CT</state>
                    <state>FL</state>
                    <state>MA</state>
                    <state>NJ</state>
                    <state>NY</state>
                    <state>OR</state>
                    <state>PA</state>
                    <state>TX</state>
                </statesOfSolicitationList>
            </recipient>
            <recipient>
                <recipientName>Lee W. Gladden</recipientName>
                <recipientCRDNumber>1821821</recipientCRDNumber>
                <associatedBDName>Sword Securities Corporation</associatedBDName>
                <associatedBDCRDNumber>32244</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>34 Chambers Street</street1>
                    <city>Princeton</city>
                    <stateOrCountry>NJ</stateOrCountry>
                    <zipCode>08540</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CA</state>
                    <state>CT</state>
                    <state>FL</state>
                    <state>MA</state>
                    <state>NJ</state>
                    <state>NY</state>
                    <state>OR</state>
                    <state>PA</state>
                    <state>TX</state>
                    <state>VA</state>
                </statesOfSolicitationList>
            </recipient>
            <recipient>
                <recipientName>William H. Sword Jr.</recipientName>
                <recipientCRDNumber>827784</recipientCRDNumber>
                <associatedBDName>Sword Securities Corporation</associatedBDName>
                <associatedBDCRDNumber>32244</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>34 Chambers Street</street1>
                    <city>Princeton</city>
                    <stateOrCountry>NJ</stateOrCountry>
                    <zipCode>08542</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CA</state>
                    <state>CT</state>
                    <state>FL</state>
                    <state>MA</state>
                    <state>NJ</state>
                    <state>NY</state>
                    <state>OR</state>
                    <state>PA</state>
                    <state>TX</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>36898000</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>25</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </findersFees>
            <clarificationOfResponse>The firms listed in Item 12 above are paid directly or indirectly commissions or similar sales compensation equal to a percentage of the fee paid to the General Partner (or its affiliate) from the assets under management and/or the incentive allocation.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>The General Partner (or its affiliate) is entitled to receive an annual management fee in an amount equal to a specified percentage of assets under management.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Amici Healthcare, L.P.</issuerName>
                <signatureName>/s/ Alpheus A. Porter</signatureName>
                <nameOfSigner>Alpheus A. Porter</nameOfSigner>
                <signatureTitle>Managing Member of the General Partner</signatureTitle>
                <signatureDate>2010-03-16</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----