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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001209191-09-059001.txt : 20091230
<SEC-HEADER>0001209191-09-059001.hdr.sgml : 20091230
<ACCEPTANCE-DATETIME>20091229215346
ACCESSION NUMBER:		0001209191-09-059001
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091230
DATE AS OF CHANGE:		20091229
EFFECTIVENESS DATE:		20091230

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ZONARE MEDICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0001259208
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-57676
		FILM NUMBER:		091264898

	BUSINESS ADDRESS:	
		STREET 1:		420 NORTH BERNARDO AVENUE
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
		BUSINESS PHONE:		6502302800

	MAIL ADDRESS:	
		STREET 1:		420 NORTH BERNARDO AVENUE
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
</SEC-HEADER>
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        <entityName>ZONARE MEDICAL SYSTEMS INC</entityName>
        <issuerAddress>
            <street1>420 North Bernardo Avenue</street1>
            <city>Mountain View</city>
            <stateOrCountry>CA</stateOrCountry>
            <zipCode>94043-1839</zipCode>
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        <issuerPhoneNumber>(650) 230-2800</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
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            <relatedPersonName>
                <firstName>Donald</firstName>
                <middleName>J.</middleName>
                <lastName>Southard</lastName>
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            <relatedPersonAddress>
                <street1>c/o ZONARE Medical Systems, Inc.</street1>
                <street2>420 North Bernardo Avenue</street2>
                <city>Mountain View</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94043-1839</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Timothy</firstName>
                <middleName>A.</middleName>
                <lastName>Marcotte</lastName>
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                <street1>c/o ZONARE Medical Systems, Inc.</street1>
                <street2>420 North Bernardo Avenue</street2>
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                <zipCode>94043-1839</zipCode>
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                <street1>c/o Frazier Healthcare Ventures</street1>
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                <stateOrCountry>WA</stateOrCountry>
                <zipCode>98101</zipCode>
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                <middleName>R.</middleName>
                <lastName>Otten</lastName>
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                <street1>c/o ZONARE Medical Systems, Inc.</street1>
                <street2>420 North Bernardo Avenue</street2>
                <city>Mountain View</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94043-1839</zipCode>
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        <relatedPersonInfo>
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                <firstName>Thomas</firstName>
                <lastName>Rasche</lastName>
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            <relatedPersonAddress>
                <street1>c/o Earlybird Verwaltungs GmbH</street1>
                <street2>Van-der-Smissen Strasse 3</street2>
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                <stateOrCountry>2M</stateOrCountry>
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                <firstName>Robert</firstName>
                <middleName>J.</middleName>
                <lastName>Gallagher</lastName>
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            <relatedPersonAddress>
                <street1>211 La Cuesta Way</street1>
                <city>Woodside</city>
                <stateOrCountry>CA</stateOrCountry>
                <zipCode>94062</zipCode>
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                <firstName>Chris</firstName>
                <lastName>Hollowood</lastName>
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            <relatedPersonAddress>
                <street1>c/o Apposite Capital LLP</street1>
                <street2>Bracken House, One Friday Street</street2>
                <city>London</city>
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                <zipCode>EC 4M 9JA</zipCode>
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                <firstName>Douglas</firstName>
                <middleName>W.</middleName>
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                <street1>c/o ZONARE Medical Systems, Inc.</street1>
                <street2>420 North Bernardo Avenue</street2>
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                <firstName>Mark</firstName>
                <middleName>M.</middleName>
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            <relatedPersonName>
                <firstName>Robert</firstName>
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            <relatedPersonRelationshipList>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001209191-09-044930</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-03-06</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>14600000</totalOfferingAmount>
            <totalAmountSold>14521736</totalAmountSold>
            <totalRemaining>78264</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>56</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
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            </salesCommissions>
            <findersFees>
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            <clarificationOfResponse></clarificationOfResponse>
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        <signatureBlock>
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            <signature>
                <issuerName>ZONARE Medical Systems Inc</issuerName>
                <signatureName>/s/ Timothy A. Marcotte</signatureName>
                <nameOfSigner>Timothy A. Marcotte</nameOfSigner>
                <signatureTitle>Vice President and Chief Financial Officer</signatureTitle>
                <signatureDate>2009-12-29</signatureDate>
            </signature>
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