-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 DtTP5IZWTXA/z8OYyVx0r35d5cMAhti1X99M5bIHGty6//fWtCYi3Ven/CdWsy/l
 8NijApjIwTXHnWWBZFfm9Q==

<SEC-DOCUMENT>0001223710-09-000006.txt : 20090701
<SEC-HEADER>0001223710-09-000006.hdr.sgml : 20090701
<ACCEPTANCE-DATETIME>20090630185721
ACCESSION NUMBER:		0001223710-09-000006
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090701
DATE AS OF CHANGE:		20090630
EFFECTIVENESS DATE:		20090701

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			METABOLON, INC
		CENTRAL INDEX KEY:			0001223710
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-53696
		FILM NUMBER:		09920340

	BUSINESS ADDRESS:	
		STREET 1:		800 CAPITOLA DRIVE
		STREET 2:		SUITE 1
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713
		BUSINESS PHONE:		919-572-1711

	MAIL ADDRESS:	
		STREET 1:		800 CAPITOLA DRIVE
		STREET 2:		SUITE 1
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	METABOLON INC
		DATE OF NAME CHANGE:	20030319
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0401</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001223710</cik>
        <entityName>METABOLON, INC</entityName>
        <issuerAddress>
            <street1>800 CAPITOLA DRIVE</street1>
            <street2>SUITE 1</street2>
            <city>DURHAM</city>
            <stateOrCountry>NC</stateOrCountry>
            <zipCode>27713</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>919-572-1711</issuerPhoneNumber>
        <issuerPreviousNameList>
            <previousName>METABOLON INC</previousName>
        </issuerPreviousNameList>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>A</middleName>
                <lastName>Ryals</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>800 Capitola Drive</street1>
                <street2>Suite 1</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27713</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jefferson</firstName>
                <middleName>B</middleName>
                <lastName>Clark</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Aurora Ventures V LLC</street1>
                <street2>2525 Meridian Parkway</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27713</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName></middleName>
                <lastName>Oxaal</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Sevin Rosen Funds</street1>
                <street2>13455 Noel Road Suite 1670</street2>
                <city>Dallas</city>
                <stateOrCountry>TX</stateOrCountry>
                <zipCode>75240</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>C</firstName>
                <middleName>Thomas</middleName>
                <lastName>Caskey</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>800 Capitola Drive</street1>
                <street2>Suite 1</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27713</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Edward</firstName>
                <middleName>L</middleName>
                <lastName>Erickson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>800 Capitola Drive</street1>
                <street2>Suite 1</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <zipCode>27713</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001223710-09-000005</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-04-30</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Robert W Baird &amp; Co Incorporated</recipientName>
                <recipientCRDNumber>8158</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>777 E Wisconsin Avenue</street1>
                    <street2></street2>
                    <city>Milwaukee</city>
                    <stateOrCountry>WI</stateOrCountry>
                    <zipCode>53202</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CA</state>
                    <state>CO</state>
                    <state>CT</state>
                    <state>DC</state>
                    <state>FL</state>
                    <state>GA</state>
                    <state>IL</state>
                    <state>IN</state>
                    <state>IA</state>
                    <state>KS</state>
                    <state>MD</state>
                    <state>MA</state>
                    <state>MN</state>
                    <state>MO</state>
                    <state>NJ</state>
                    <state>NY</state>
                    <state>NC</state>
                    <state>OH</state>
                    <state>OR</state>
                    <state>PA</state>
                    <state>TN</state>
                    <state>TX</state>
                    <state>UT</state>
                    <state>VA</state>
                    <state>WA</state>
                    <state>WI</state>
                    <state>WY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>11020577</totalOfferingAmount>
            <totalAmountSold>6273642</totalAmountSold>
            <totalRemaining>4746935</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>7</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>50000</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>Other than the payment of salaries and other compensation and benefits, no officer, director or promoter will receive any payments from the proceeds of this offering.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>METABOLON, INC</issuerName>
                <signatureName>S Todd Lynch</signatureName>
                <nameOfSigner>S Todd Lynch</nameOfSigner>
                <signatureTitle>CFO and Secretary</signatureTitle>
                <signatureDate>2009-06-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----