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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001156996-10-000001.txt : 20100630
<SEC-HEADER>0001156996-10-000001.hdr.sgml : 20100630
<ACCEPTANCE-DATETIME>20100629174802
ACCESSION NUMBER:		0001156996-10-000001
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100630
DATE AS OF CHANGE:		20100629
EFFECTIVENESS DATE:		20100630

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PNEUMOFLEX SYSTEMS LLC
		CENTRAL INDEX KEY:			0001156996
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-46128
		FILM NUMBER:		10924952

	BUSINESS ADDRESS:	
		STREET 1:		101 EAST FLORIDA AVENUE
		CITY:			MELBOURNE
		STATE:			FL
		ZIP:			32901
		BUSINESS PHONE:		321 984 4628

	MAIL ADDRESS:	
		STREET 1:		101 EAST FLORIDA AVENUE
		CITY:			MELBOURNE
		STATE:			FL
		ZIP:			32901
</SEC-HEADER>
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<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
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        <entityName>PNEUMOFLEX SYSTEMS LLC</entityName>
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            <street1>101 EAST FLORIDA AVENUE</street1>
            <city>MELBOURNE</city>
            <stateOrCountry>FL</stateOrCountry>
            <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
            <zipCode>32901</zipCode>
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        <issuerPhoneNumber>321 984 4628</issuerPhoneNumber>
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            <relatedPersonName>
                <firstName>W</firstName>
                <middleName>Robert</middleName>
                <lastName>Addington, II, D.O.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o 101 East Florida Avenue</street1>
                <city>Melbourne</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>32901</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Member of the Board of Managers</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <middleName>P.</middleName>
                <lastName>Kennedy</lastName>
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                <street1>c/o 101 East Florida Avenue</street1>
                <city>Melbourne</city>
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                <zipCode>32901</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>E.</middleName>
                <lastName>Stephens, Ph.D.</lastName>
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                <zipCode>32901</zipCode>
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                <lastName>Miller, M.D.</lastName>
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                <street1>c/o 101 East Florida Avenue</street1>
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                <zipCode>32901</zipCode>
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                <lastName>Rasmussen, Ed D</lastName>
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            <relatedPersonRelationshipList>
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            <relationshipClarification>Member of the Board of Managers</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Albert</firstName>
                <middleName>F.</middleName>
                <lastName>Stevens</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o 101 East Florida Avenue</street1>
                <city>Melbourne</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>32901</zipCode>
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            <relatedPersonRelationshipList>
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            <relationshipClarification>Member of the Board of Managers</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Daniel</firstName>
                <middleName>L.</middleName>
                <lastName>Villanueva</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o 101 East Florida Avenue</street1>
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                <zipCode>32901</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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        <relatedPersonInfo>
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                <firstName>David</firstName>
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                <street1>c/o 101 East Florida Avenue</street1>
                <city>Melbourne</city>
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                <zipCode>32901</zipCode>
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        <relatedPersonInfo>
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                <firstName>John</firstName>
                <lastName>Crysel</lastName>
            </relatedPersonName>
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                <street1>c/o 101 East Florida Avenue</street1>
                <city>Melbourne</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>32901</zipCode>
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            <relatedPersonRelationshipList>
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        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>na</firstName>
                <lastName>Pneumoflex Systems, Inc.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>101 East Florida Avenue</street1>
                <city>Melbourne</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>32901</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Controlling Member of the Issuer</relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001156996-09-000003</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-11-09</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>1</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>9500000</totalOfferingAmount>
            <totalAmountSold>930000</totalAmountSold>
            <totalRemaining>8570000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>14</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
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        <useOfProceeds>
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                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>PNEUMOFLEX SYSTEMS LLC</issuerName>
                <signatureName>Stuart P. Miller</signatureName>
                <nameOfSigner>Stuart P. Miller</nameOfSigner>
                <signatureTitle>Treasurer</signatureTitle>
                <signatureDate>2010-06-29</signatureDate>
            </signature>
        </signatureBlock>
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