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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001013762-09-002255.txt : 20091207
<SEC-HEADER>0001013762-09-002255.hdr.sgml : 20091207
<ACCEPTANCE-DATETIME>20091207111205
ACCESSION NUMBER:		0001013762-09-002255
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091207
DATE AS OF CHANGE:		20091207
EFFECTIVENESS DATE:		20091207

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ADVANCED CELL TECHNOLOGY, INC.
		CENTRAL INDEX KEY:			0001140098
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870656515
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-96793
		FILM NUMBER:		091225279

	BUSINESS ADDRESS:	
		STREET 1:		381 PLANTATION STREET
		CITY:			WORCESTER
		STATE:			MA
		ZIP:			01605
		BUSINESS PHONE:		508-756-1212

	MAIL ADDRESS:	
		STREET 1:		381 PLANTATION STREET
		CITY:			WORCESTER
		STATE:			MA
		ZIP:			01605

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	A.C.T. Holdings, Inc.
		DATE OF NAME CHANGE:	20050303

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	A.C.T Holdings, Inc.
		DATE OF NAME CHANGE:	20050207

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ACT Holdings Inc.
		DATE OF NAME CHANGE:	20050204
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001140098</cik>
        <entityName>ADVANCED CELL TECHNOLOGY, INC.</entityName>
        <issuerAddress>
            <street1>381 PLANTATION STREET</street1>
            <city>WORCESTER</city>
            <stateOrCountry>MA</stateOrCountry>
            <zipCode>01605</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>508-756-1212</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>A.C.T. Holdings, Inc.</previousName>
            <previousName>A.C.T Holdings, Inc.</previousName>
            <previousName>ACT Holdings Inc.</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <middleName>M.</middleName>
                <lastName>Cladwell</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>381 Plantation Street</street1>
                <city>Worcester</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01605</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Erkki</firstName>
                <lastName>Ruoslahti</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>381 Plantation Street</street1>
                <city>Worcester</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01605</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gary</firstName>
                <lastName>Rabin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>381 Plantation Street</street1>
                <city>Worcester</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01605</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Alan</firstName>
                <middleName>C.</middleName>
                <lastName>Shapiro</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>381 Plantation Street</street1>
                <city>Worcester</city>
                <stateOrCountry>MA</stateOrCountry>
                <zipCode>01605</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$1 - $1,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-11-12</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>100000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>2777000</totalOfferingAmount>
            <totalAmountSold>2777000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>Includes $1,385,000 of securities sold at the initial closing on November 12, 2009, and November 13, 2009 and $1,385,000 of securities the investors agreed to purchase, subject to customary conditions, within 90 days of initial closing.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>10</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>ADVANCED CELL TECHNOLOGY, INC.</issuerName>
                <signatureName>/s/ William M. Caldwell, IV</signatureName>
                <nameOfSigner>William M. Caldwell, IV</nameOfSigner>
                <signatureTitle>Chief Executive Officer</signatureTitle>
                <signatureDate>2009-12-07</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----