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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 AMd5z8sn7m+gD0wJmcuOmA==

<SEC-DOCUMENT>0001138318-10-000007.txt : 20101213
<SEC-HEADER>0001138318-10-000007.hdr.sgml : 20101213
<ACCEPTANCE-DATETIME>20101213122937
ACCESSION NUMBER:		0001138318-10-000007
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20101213
DATE AS OF CHANGE:		20101213
EFFECTIVENESS DATE:		20101213

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pathogenetix, Inc.
		CENTRAL INDEX KEY:			0001138318
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-149968
		FILM NUMBER:		101247234

	BUSINESS ADDRESS:	
		STREET 1:		12 GILL STREET, SUITE 4700
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801
		BUSINESS PHONE:		7819375550

	MAIL ADDRESS:	
		STREET 1:		12 GILL STREET, SUITE 4700
		CITY:			WOBURN
		STATE:			MA
		ZIP:			01801

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	US GENOMICS INC
		DATE OF NAME CHANGE:	20010413
</SEC-HEADER>
<DOCUMENT>
<TYPE>D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001138318</cik>
        <entityName>Pathogenetix, Inc.</entityName>
        <issuerAddress>
            <street1>12 GILL STREET, SUITE 4700</street1>
            <city>WOBURN</city>
            <stateOrCountry>MA</stateOrCountry>
            <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
            <zipCode>01801</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>7819375550</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>US GENOMICS INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>JOHN</firstName>
                <middleName>J.</middleName>
                <lastName>CANEPA</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>C/O Pathogenetix, Inc.</street1>
                <street2>12 GILL STREET, SUITE 3850</street2>
                <city>WOBURN</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>01801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>AUGUSTINE</firstName>
                <lastName>LAWLOR</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>C/O Pathogenetix, Inc.</street1>
                <street2>12 GILL STREET, SUITE 3850</street2>
                <city>WOBURN</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>01801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>STEPHEN</firstName>
                <lastName>GULLANS</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>C/O U.S. GENOMICS, INC.</street1>
                <street2>12 GILL STREET, SUITE 3850</street2>
                <city>WOBURN</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>01801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>DAVID</firstName>
                <lastName>HOEY</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>C/O Pathogenetix, Inc.</street1>
                <street2>12 GILL STREET, SUITE 3850</street2>
                <city>WOBURN</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>01801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>ENRICO</firstName>
                <lastName>PETRILLO</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>C/O Pathogenetix, Inc.</street1>
                <street2>12 GILL STREET, SUITE 3850</street2>
                <city>WOBURN</city>
                <stateOrCountry>MA</stateOrCountry>
                <stateOrCountryDescription>MASSACHUSETTS</stateOrCountryDescription>
                <zipCode>01801</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001138318-10-000005</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-10-20</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1810453</totalOfferingAmount>
            <totalAmountSold>1510453</totalAmountSold>
            <totalRemaining>300000</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>5</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Pathogenetix, Inc.</issuerName>
                <signatureName>/s/ John J. Canepa</signatureName>
                <nameOfSigner>JOHN J. CANEPA</nameOfSigner>
                <signatureTitle>PRESIDENT AND CHIEF EXECUTIVE OFFICER</signatureTitle>
                <signatureDate>2010-12-13</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----