-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 PHxPiOz6t04tLg5Fngu7DuwZeFJadDvDPQSoj8mVq2iOMOakJ4rsNFH5zM3pwm7L
 ARwDqdW5HUkLsTpDFMifYA==

<SEC-DOCUMENT>0001131816-10-000001.txt : 20100217
<SEC-HEADER>0001131816-10-000001.hdr.sgml : 20100217
<ACCEPTANCE-DATETIME>20100217160419
ACCESSION NUMBER:		0001131816-10-000001
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100217
DATE AS OF CHANGE:		20100217
EFFECTIVENESS DATE:		20100217

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MARKET SCIENCE, INC.
		CENTRAL INDEX KEY:			0001131816
		IRS NUMBER:				233064118
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-44864
		FILM NUMBER:		10612858

	BUSINESS ADDRESS:	
		STREET 1:		2700 HORIZON DRIVE
		STREET 2:		SUITE 200
		CITY:			KING OF PRUSSIA
		STATE:			PA
		ZIP:			19406
		BUSINESS PHONE:		8005934467

	MAIL ADDRESS:	
		STREET 1:		2700 HORIZON DRIVE
		STREET 2:		SUITE 200
		CITY:			KING OF PRUSSIA
		STATE:			PA
		ZIP:			19406

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MARKET SCIENCE INC
		DATE OF NAME CHANGE:	20010108
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001131816</cik>
        <entityName>MARKET SCIENCE, INC.</entityName>
        <issuerAddress>
            <street1>2700 HORIZON DRIVE</street1>
            <street2>SUITE 200</street2>
            <city>KING OF PRUSSIA</city>
            <stateOrCountry>PA</stateOrCountry>
            <zipCode>19406</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>8005934467</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>MARKET SCIENCE INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Martinson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1009 Lenox Drive #4</street1>
                <city>Lawrenceville</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08648</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ron</firstName>
                <lastName>Cacciola</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>105 East 17th Street</street1>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10003</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gregory</firstName>
                <lastName>Mistele</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>101 Columbia Road</street1>
                <city>Morristown</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>07962</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <lastName>Wray</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Five Tower Bridge</street1>
                <street2>300 Barr Harbor Drive, Suite 400</street2>
                <city>West Conshohocken</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19428</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Matthew</firstName>
                <middleName>C</middleName>
                <lastName>Reichert</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2700 Horizon Drive</street1>
                <street2>Suite 200</street2>
                <city>King of Prussia</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19406</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Executive Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Vincent</firstName>
                <middleName>T</middleName>
                <lastName>Dolan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2700 Horizon Drive</street1>
                <street2>Suite 200</street2>
                <city>King of Prussia</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19406</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Financial Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <lastName>Ryan</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2700 Horizon Drive</street1>
                <street2>Suite 200</street2>
                <city>King of Prussia</city>
                <stateOrCountry>PA</stateOrCountry>
                <zipCode>19406</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Technology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$25,000,001 - $100,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-02-16</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>4798</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>2000000</totalOfferingAmount>
            <totalAmountSold>2000000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>9</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MARKET SCIENCE, INC.</issuerName>
                <signatureName>/s</signatureName>
                <nameOfSigner>Matthew C. Reichert</nameOfSigner>
                <signatureTitle>Chief Executive Officer</signatureTitle>
                <signatureDate>2010-02-17</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----