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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001503788-10-000002.txt : 20101115
<SEC-HEADER>0001503788-10-000002.hdr.sgml : 20101115
<ACCEPTANCE-DATETIME>20101115162015
ACCESSION NUMBER:		0001503788-10-000002
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20101115
DATE AS OF CHANGE:		20101115
EFFECTIVENESS DATE:		20101115

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Advaxis, Inc.
		CENTRAL INDEX KEY:			0001100397
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841521955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-150531
		FILM NUMBER:		101192713

	BUSINESS ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902
		BUSINESS PHONE:		732 545 1590

	MAIL ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREAT EXPECTATIONS & ASSOCIATES INC
		DATE OF NAME CHANGE:	19991203
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001100397</cik>
        <entityName>Advaxis, Inc.</entityName>
        <issuerAddress>
            <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
            <street2>675 ROUTE 1</street2>
            <city>NORTH BRUNSWICK</city>
            <stateOrCountry>NJ</stateOrCountry>
            <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
            <zipCode>08902</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>732 545 1590</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>GREAT EXPECTATIONS AND ASSOCIATES, INC.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <previousName>GREAT EXPECTATIONS &amp; ASSOCIATES INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>THOMAS</firstName>
                <lastName>MOORE</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>JAMES</firstName>
                <lastName>PATTON</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>RONI</firstName>
                <middleName>A.</middleName>
                <lastName>APPEL</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>THOMAS</firstName>
                <lastName>MCKEARN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>RICHARD</firstName>
                <lastName>BERMAN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>JOHN</firstName>
                <lastName>ROTHMAN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>MARK</firstName>
                <middleName>J.</middleName>
                <lastName>ROSENBLUM</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-11-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Common Stock issuable upon conversion of notes.</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Matthew D. Eitner</recipientName>
                <recipientCRDNumber>3267261</recipientCRDNumber>
                <associatedBDName>Laidlaw &amp; Company (UK) Ltd.</associatedBDName>
                <associatedBDCRDNumber>119037</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>546 5th Avenue</street1>
                    <street2>5th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10036</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>FL</state>
                    <description>FLORIDA</description>
                    <state>NJ</state>
                    <description>NEW JERSEY</description>
                    <state>NC</state>
                    <description>NORTH CAROLINA</description>
                    <state>OK</state>
                    <description>OKLAHOMA</description>
                    <state>PA</state>
                    <description>PENNSYLVANIA</description>
                    <state>TX</state>
                    <description>TEXAS</description>
                    <state>WA</state>
                    <description>WASHINGTON</description>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Evan Greenberg</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>11 Hunters Lane</street1>
                    <city>Roslyn</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>11576</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>CA</state>
                    <description>CALIFORNIA</description>
                    <state>IA</state>
                    <description>IOWA</description>
                    <state>NY</state>
                    <description>NEW YORK</description>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>835000</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>10</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>50250</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>No amount of the gross proceeds is anticipated to pay named executive officers, except that the issuer may use the gross proceeds or other available funds for payments to the chief executive officer for the amounts owed to him of not less than $538,791.00</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Advaxis, Inc.</issuerName>
                <signatureName>Mark J. Rosenblum</signatureName>
                <nameOfSigner>MARK J. ROSENBLUM</nameOfSigner>
                <signatureTitle>Chief Financial Officer, Senior Vice President and Secretary</signatureTitle>
                <signatureDate>2010-11-12</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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