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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001448051-09-000008.txt : 20091022
<SEC-HEADER>0001448051-09-000008.hdr.sgml : 20091022
<ACCEPTANCE-DATETIME>20091022150803
ACCESSION NUMBER:		0001448051-09-000008
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091022
DATE AS OF CHANGE:		20091022
EFFECTIVENESS DATE:		20091022

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Advaxis, Inc.
		CENTRAL INDEX KEY:			0001100397
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841521955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-73969
		FILM NUMBER:		091132372

	BUSINESS ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902
		BUSINESS PHONE:		732 545 1590

	MAIL ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREAT EXPECTATIONS & ASSOCIATES INC
		DATE OF NAME CHANGE:	19991203
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001100397</cik>
        <entityName>Advaxis, Inc.</entityName>
        <issuerAddress>
            <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
            <street2>675 ROUTE 1</street2>
            <city>NORTH BRUNSWICK</city>
            <stateOrCountry>NJ</stateOrCountry>
            <zipCode>08902</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>732 545 1590</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>GREAT EXPECTATIONS &amp; ASSOCIATES INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <middleName>A.</middleName>
                <lastName>Moore</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Fredrick</firstName>
                <lastName>Cobb</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>M.</middleName>
                <lastName>Rothman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Roni</firstName>
                <lastName>Appel</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <lastName>McKearn</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <lastName>Patton</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <lastName>Berman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-10-07</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Evan Greenberg</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>11 Hunter Lane</street1>
                    <city>Roslyn</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>11576</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>50000</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>2500</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>1110692</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>Represents deferred salary and principal amount of a promissory note that the issuer owes the chief executive officer.  The issuer may use the gross proceeds or other available funds for payments to the chief executive officer for the amounts owed to him.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Advaxis, Inc.</issuerName>
                <signatureName>Thomas A. Moore</signatureName>
                <nameOfSigner>Thomas A. Moore</nameOfSigner>
                <signatureTitle>Chief Executive Officer</signatureTitle>
                <signatureDate>2009-10-22</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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