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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001321620-09-000006.txt : 20091001
<SEC-HEADER>0001321620-09-000006.hdr.sgml : 20091001
<ACCEPTANCE-DATETIME>20091001130327
ACCESSION NUMBER:		0001321620-09-000006
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091001
DATE AS OF CHANGE:		20091001
EFFECTIVENESS DATE:		20091001

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Advaxis, Inc.
		CENTRAL INDEX KEY:			0001100397
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841521955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-73969
		FILM NUMBER:		091097933

	BUSINESS ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902
		BUSINESS PHONE:		732 545 1590

	MAIL ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREAT EXPECTATIONS & ASSOCIATES INC
		DATE OF NAME CHANGE:	19991203
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001100397</cik>
        <entityName>Advaxis, Inc.</entityName>
        <issuerAddress>
            <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
            <street2>675 ROUTE 1</street2>
            <city>NORTH BRUNSWICK</city>
            <stateOrCountry>NJ</stateOrCountry>
            <zipCode>08902</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>732 545 1590</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>GREAT EXPECTATIONS &amp; ASSOCIATES INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <middleName>A.</middleName>
                <lastName>Moore</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Fredrick</firstName>
                <lastName>Cobb</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName>M.</middleName>
                <lastName>Rothman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Roni</firstName>
                <lastName>Appel</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <lastName>McKearn</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <lastName>Patton</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <lastName>Berman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Technology Centre of New Jersey</street1>
                <street2>675 Rt. 1</street2>
                <city>North Brunswick</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-06-17</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>John Carter Lipman</recipientName>
                <recipientCRDNumber>3080448</recipientCRDNumber>
                <associatedBDName>Carter Securities, LLC</associatedBDName>
                <associatedBDCRDNumber>136350</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>215 East 68th Street, Apt. 25G</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <zipCode>10065</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                </statesOfSolicitationList>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>961650</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>7</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>12000</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>185692</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>Represents deferred salary that the issuer owes the chief executive officer, which is payable from the gross proceeds if certain amounts are raised in the offering as set forth in a Note Purchase Agreement.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Advaxis, Inc.</issuerName>
                <signatureName>Thomas A. Moore</signatureName>
                <nameOfSigner>Thomas A. Moore</nameOfSigner>
                <signatureTitle>Chief Executive Officer</signatureTitle>
                <signatureDate>2009-09-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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