-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 CEfQ68yyIuic3Gz86UHKZDp6zO0PjgpkokGa2aSEG+ZUM7Y00BIa2s7fJatS7r0C
 dHCdSSjLYyRXy0O7XAwqBA==

<SEC-DOCUMENT>0001144204-10-040463.txt : 20100730
<SEC-HEADER>0001144204-10-040463.hdr.sgml : 20100730
<ACCEPTANCE-DATETIME>20100730170948
ACCESSION NUMBER:		0001144204-10-040463
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100730
DATE AS OF CHANGE:		20100730
EFFECTIVENESS DATE:		20100730

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Advaxis, Inc.
		CENTRAL INDEX KEY:			0001100397
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841521955
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-145752
		FILM NUMBER:		10981911

	BUSINESS ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902
		BUSINESS PHONE:		732 545 1590

	MAIL ADDRESS:	
		STREET 1:		TECHNOLOGY CENTRE OF NEW JERSEY
		STREET 2:		675 ROUTE 1
		CITY:			NORTH BRUNSWICK
		STATE:			NJ
		ZIP:			08902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREAT EXPECTATIONS & ASSOCIATES INC
		DATE OF NAME CHANGE:	19991203
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001100397</cik>
        <entityName>Advaxis, Inc.</entityName>
        <issuerAddress>
            <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
            <street2>675 ROUTE 1</street2>
            <city>NORTH BRUNSWICK</city>
            <stateOrCountry>NJ</stateOrCountry>
            <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
            <zipCode>08902</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>732-545-1590</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>GREAT EXPECTATIONS AND ASSOCIATES, INC.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <previousName>GREAT EXPECTATIONS &amp; ASSOCIATES INC</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>THOMAS</firstName>
                <lastName>MOORE</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>JAMES</firstName>
                <lastName>PATTON</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>RONI</firstName>
                <middleName>A.</middleName>
                <lastName>APPEL</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>THOMAS</firstName>
                <lastName>MCKEARN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>RICHARD</firstName>
                <lastName>BERMAN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>JOHN</firstName>
                <lastName>ROTHMAN</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>MARK</firstName>
                <middleName>J.</middleName>
                <lastName>ROSENBLUM</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>TECHNOLOGY CENTRE OF NEW JERSEY</street1>
                <street2>675 Route 1</street2>
                <city>NORTH BRUNSWICK</city>
                <stateOrCountry>NJ</stateOrCountry>
                <stateOrCountryDescription>NEW JERSEY</stateOrCountryDescription>
                <zipCode>08902</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-07-19</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>7500000</totalOfferingAmount>
            <totalAmountSold>7500000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Advaxis, Inc.</issuerName>
                <signatureName>/s/ MARK J. ROSENBLUM</signatureName>
                <nameOfSigner>MARK J. ROSENBLUM</nameOfSigner>
                <signatureTitle>Chief Financial Officer, Senior Vice President and Secretary</signatureTitle>
                <signatureDate>2010-07-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----