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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 KaDvfhE4qWOicrODtdu42ht33E11Wer7ti4faLinUj10lWxRz+zdkkq8CPf0aqTm
 U+/Xi9mKS9JIwuY4csf7fQ==

<SEC-DOCUMENT>0001070081-09-000003.txt : 20091222
<SEC-HEADER>0001070081-09-000003.hdr.sgml : 20091222
<ACCEPTANCE-DATETIME>20091222170635
ACCESSION NUMBER:		0001070081-09-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20091222
DATE AS OF CHANGE:		20091222
EFFECTIVENESS DATE:		20091222

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PTC THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001070081
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043416587
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-61608
		FILM NUMBER:		091255808

	BUSINESS ADDRESS:	
		STREET 1:		100 CORPORATE COURT
		CITY:			SOUTH PLAINFIELD
		STATE:			NJ
		ZIP:			07080-2449
		BUSINESS PHONE:		9082227000

	MAIL ADDRESS:	
		STREET 1:		100 CORPORATE COURT
		CITY:			SOUTH PLAINFIELD
		STATE:			NJ
		ZIP:			07080-2449

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PTC THERAPEUTICS INC
		DATE OF NAME CHANGE:	19980909
</SEC-HEADER>
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<SEQUENCE>1
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            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Schmertzler</lastName>
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            <relatedPersonAddress>
                <street1>c/o Credit Suisse First Boston</street1>
                <street2>11 Madison Avenue</street2>
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            <relatedPersonName>
                <firstName>Carl</firstName>
                <lastName>Goldfischer</lastName>
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            <relatedPersonAddress>
                <street1>c/o Bay City Capital Fund III LP</street1>
                <street2>750 Battery Street</street2>
                <city>San Francisco</city>
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                <firstName>Soren</firstName>
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                <street1>c/o Novo A/S</street1>
                <street2>Krogshoejvej 41</street2>
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                <firstName>Axel</firstName>
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                <street1>c/o HBM Partners AG</street1>
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                <firstName>Deepa</firstName>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$25,000,001 - $100,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
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            <dateOfFirstSale>
                <value>2009-12-22</value>
            </dateOfFirstSale>
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        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
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        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
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        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>50300000</totalOfferingAmount>
            <totalAmountSold>25150064</totalAmountSold>
            <totalRemaining>25149936</totalRemaining>
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        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>21</totalNumberAlreadyInvested>
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        <salesCommissionsFindersFees>
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                <issuerName>PTC THERAPEUTICS, INC.</issuerName>
                <signatureName>/s/ Mark E. Boulding</signatureName>
                <nameOfSigner>Mark E. Boulding</nameOfSigner>
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-----END PRIVACY-ENHANCED MESSAGE-----